Metabolic Catastrophe in Mice Lacking Transferrin Receptor in Muscle
Transferrin receptor (Tfr1) is ubiquitously expressed, but its roles in non-hematopoietic cells are incompletely understood. We used a tissue-specific conditional knockout strategy to ask whether skeletal muscle required Tfr1 for iron uptake. We found that iron assimilation via Tfr1 was critical for...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Elsevier
2015
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740293/ |