Mathematical modelling of the automated FADU assay for the quantification of DNA strand breaks and their repair in human peripheral mononuclear blood cells

by Junk, Michael, Salzwedel, Judy, Sindlinger, Thilo, Bürkle, Alexander, Moreno-Villanueva, Maria
Published 2014

Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8+ T cells sensitizing them to apoptotic cell death

by Brunner, Stefan, Herndler-Brandstetter, Dietmar, Arnold, Christoph R, Wiegers, Gerrit Jan, Villunger, Andreas, Hackl, Matthias, Grillari, Johannes, Moreno-Villanueva, María, Bürkle, Alexander, Grubeck-Loebenstein, Beatrix
Published 2012

Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients

by Maynard, Scott, Hejl, Anne-Mette, Dinh, Thuan-Son T., Keijzers, Guido, Hansen, Åse M., Desler, Claus, Moreno-Villanueva, Maria, Bürkle, Alexander, Rasmussen, Lene J., Waldemar, Gunhild, Bohr, Vilhelm A.
Published 2015

Structural chromosome abnormalities, increased DNA strand breaks and DNA strand break repair deficiency in dermal fibroblasts from old female human donors

by Kalfalah, Faiza, Seggewiß, Sabine, Walter, Regina, Tigges, Julia, Moreno-Villanueva, María, Bürkle, Alexander, Ohse, Sebastian, Busch, Hauke, Boerries, Melanie, Hildebrandt, Barbara, Royer-Pokora, Brigitte, Boege, Fritz
Published 2015

High-Resolution Quantitative Metabolome Analysis of Urine by Automated Flow Injection NMR

by Da Silva, Laeticia, Godejohann, Markus, Martin, François-Pierre J., Collino, Sebastiano, Bürkle, Alexander, Moreno-Villanueva, María, Bernhardt, Jürgen, Toussaint, Olivier, Grubeck-Loebenstein, Beatrix, Gonos, Efstathios S., Sikora, Ewa, Grune, Tilman, Breusing, Nicolle, Franceschi, Claudio, Hervonen, Antti, Spraul, Manfred, Moco, Sofia
Published 2013

Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35–74 Years) General Population: A Cross-Sectional Study in Six European Countries

by Stuetz, Wolfgang, Weber, Daniela, Dollé, Martijn E. T., Jansen, Eugène, Grubeck-Loebenstein, Beatrix, Fiegl, Simone, Toussaint, Olivier, Bernhardt, Juergen, Gonos, Efstathios S., Franceschi, Claudio, Sikora, Ewa, Moreno-Villanueva, María, Breusing, Nicolle, Grune, Tilman, Bürkle, Alexander
Published 2016

The Role of Nibrin in Doxorubicin-Induced Apoptosis and Cell Senescence in Nijmegen Breakage Syndrome Patients Lymphocytes

by Alster, Olga, Bielak-Zmijewska, Anna, Mosieniak, Grazyna, Moreno-Villanueva, Maria, Dudka-Ruszkowska, Wioleta, Wojtala, Aleksandra, Kusio-Kobiałka, Monika, Korwek, Zbigniew, Burkle, Alexander, Piwocka, Katarzyna, Siwicki, Jan K., Sikora, Ewa
Published 2014

Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study

by Valentini, Elisabetta, Zampieri, Michele, Malavolta, Marco, Bacalini, Maria Giulia, Calabrese, Roberta, Guastafierro, Tiziana, Reale, Anna, Franceschi, Claudio, Hervonen, Antti, Koller, Bernhard, Bernhardt, Jürgen, Slagboom, P. Eline, Toussaint, Olivier, Sikora, Ewa, Gonos, Efstathios S., Breusing, Nicolle, Grune, Tilman, Jansen, Eugène, Dollé, Martijn E.T., Moreno-Villanueva, María, Sindlinger, Thilo, Bürkle, Alexander, Ciccarone, Fabio, Caiafa, Paola
Published 2016

Age‐dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK‐AGE study

by Ciccarone, Fabio, Malavolta, Marco, Calabrese, Roberta, Guastafierro, Tiziana, Bacalini, Maria Giulia, Reale, Anna, Franceschi, Claudio, Capri, Miriam, Hervonen, Antti, Hurme, Mikko, Grubeck‐Loebenstein, Beatrix, Koller, Bernhard, Bernhardt, Jürgen, Schӧn, Christiane, Slagboom, P. Eline, Toussaint, Olivier, Sikora, Ewa, Gonos, Efstathios S., Breusing, Nicolle, Grune, Tilman, Jansen, Eugène, Dollé, Martijn, Moreno‐Villanueva, María, Sindlinger, Thilo, Bürkle, Alexander, Zampieri, Michele, Caiafa, Paola
Published 2016

Relationship between genome and epigenome - challenges and requirements for future research

by Almouzni, Geneviève, Altucci, Lucia, Amati, Bruno, Ashley, Neil, Baulcombe, David, Beaujean, Nathalie, Bock, Christoph, Bongcam-Rudloff, Erik, Bousquet, Jean, Braun, Sigurd, Paillerets, Brigitte Bressac-de, Bussemakers, Marion, Clarke, Laura, Conesa, Ana, Estivill, Xavier, Fazeli, Alireza, Grgurević, Neža, Gut, Ivo, Heijmans, Bastiaan T, Hermouet, Sylvie, Houwing–Duistermaat, Jeanine, Iacobucci, Ilaria, Ilaš, Janez, Kandimalla, Raju, Krauss-Etschmann, Susanne, Lasko, Paul, Lehmann, Sören, Lindroth, Anders, Majdič, Gregor, Marcotte, Eric, Martinelli, Giovanni, Martinet, Nadine, Meyer, Eric, Miceli, Cristina, Mills, Ken, Moreno-Villanueva, Maria, Morvan, Ghislaine, Nickel, Dörthe, Niesler, Beate, Nowacki, Mariusz, Nowak, Jacek, Ossowski, Stephan, Pelizzola, Mattia, Pochet, Roland, Potočnik, Uroš, Radwanska, Magdalena, Raes, Jeroen, Rattray, Magnus, Robinson, Mark D, Roelen, Bernard, Sauer, Sascha, Schinzer, Dieter, Slagboom, Eline, Spector, Tim, Stunnenberg, Hendrik G, Tiligada, Ekaterini, Torres-Padilla, Maria-Elena, Tsonaka, Roula, Soom, Ann Van, Vidaković, Melita, Widschwendter, Martin
Published 2014