Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8+ T cells sensitizing them to apoptotic cell death

Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8+ T cells sensitizing them to apoptotic cell death

The life-long homeostasis of memory CD8+ T cells as well as persistent viral infections have been shown to facilitate the accumulation of highly differentiated CD8+CD28− T cells, a phenomenon that has been associated with an impaired immune function in humans. However, the molecular mechanisms regul...

Full description

Bibliographic Details
Main Authors: Brunner, Stefan, Herndler-Brandstetter, Dietmar, Arnold, Christoph R, Wiegers, Gerrit Jan, Villunger, Andreas, Hackl, Matthias, Grillari, Johannes, Moreno-Villanueva, María, Bürkle, Alexander, Grubeck-Loebenstein, Beatrix
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427896/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427896/

Similar Items