Postprimary Tuberculosis and Macrophage Necrosis: Is There a Big ConNECtion?

by Wong, Ka-Wing, Jacobs, William R.
Published 2016

Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reaction

by Vilchèze, Catherine, Hartman, Travis, Weinrick, Brian, Jacobs, William R.
Published 2013

Oligomers of Heat-Shock Proteins: Structures That Don’t Imply Function

by Jacobs, William M., Knowles, Tuomas P. J., Frenkel, Daan
Published 2016

A Mycobacterium tuberculosis Cytochrome bd Oxidase Mutant Is Hypersensitive to Bedaquiline

by Berney, Michael, Hartman, Travis E., Jacobs, William R.
Published 2014

Formulation of a mmaA4 Gene Deletion Mutant of Mycobacterium bovis BCG in Cationic Liposomes Significantly Enhances Protection against Tuberculosis

by Derrick, Steven C., Dao, Dee, Yang, Amy, Kolibab, Kris, Jacobs, William R., Morris, Sheldon L.
Published 2012

Priming with Recombinant Auxotrophic BCG Expressing HIV-1 Gag, RT and Gp120 and Boosting with Recombinant MVA Induces a Robust T Cell Response in Mice

by Chapman, Rosamund, Stutz, Helen, Jacobs, William, Shephard, Enid, Williamson, Anna-Lise
Published 2013

Succinate Dehydrogenase is the Regulator of Respiration in Mycobacterium tuberculosis

by Hartman, Travis, Weinrick, Brian, Vilchèze, Catherine, Berney, Michael, Tufariello, Joanne, Cook, Gregory M., Jacobs, William R.
Published 2014

Essentiality of Succinate Dehydrogenase in Mycobacterium smegmatis and Its Role in the Generation of the Membrane Potential Under Hypoxia

by Pecsi, Ildiko, Hards, Kiel, Ekanayaka, Nandula, Berney, Michael, Hartman, Travis, Jacobs, William R., Cook, Gregory M.
Published 2014

Mechanism of thioamide drug action against tuberculosis and leprosy

by Wang, Feng, Langley, Robert, Gulten, Gulcin, Dover, Lynn G., Besra, Gurdyal S., Jacobs, William R., Sacchettini, James C.
Published 2007

Priming with a Recombinant Pantothenate Auxotroph of Mycobacterium bovis BCG and Boosting with MVA Elicits HIV-1 Gag Specific CD8+ T Cells

by Chapman, Rosamund, Shephard, Enid, Stutz, Helen, Douglass, Nicola, Sambandamurthy, Vasan, Garcia, Irene, Ryffel, Bernhard, Jacobs, William, Williamson, Anna-Lise
Published 2012

Acetic Acid, the Active Component of Vinegar, Is an Effective Tuberculocidal Disinfectant

by Cortesia, Claudia, Vilchèze, Catherine, Bernut, Audrey, Contreras, Whendy, Gómez, Keyla, de Waard, Jacobus, Jacobs, William R., Kremer, Laurent, Takiff, Howard
Published 2014

Malaria Infections Do Not Compromise Vaccine-Induced Immunity against Tuberculosis in Mice

by Parra, Marcela, Derrick, Steven C., Yang, Amy, Tian, JinHua, Kolibab, Kristopher, Oakley, Miranda, Perera, Liyanage P., Jacobs, William R., Kumar, Sanjai, Morris, Sheldon L.
Published 2011

Mycobacterium tuberculosis nuoG Is a Virulence Gene That Inhibits Apoptosis of Infected Host Cells

by Velmurugan, Kamalakannan, Chen, Bing, Miller, Jessica L, Azogue, Sharon, Gurses, Serdar, Hsu, Tsungda, Glickman, Michael, Jacobs, William R, Porcelli, Steven A, Briken, Volker
Published 2007

Oleic Acid Biosynthesis in Plasmodium falciparum: Characterization of the Stearoyl-CoA Desaturase and Investigation as a Potential Therapeutic Target

by Gratraud, Paul, Huws, Enlli, Falkard, Brie, Adjalley, Sophie, Fidock, David A., Berry, Laurence, Jacobs, William R., Baird, Mark S., Vial, Henri, Kremer, Laurent
Published 2009

Keto-Mycolic Acid-Dependent Pellicle Formation Confers Tolerance to Drug-Sensitive Mycobacterium tuberculosis

by Sambandan, Dhinakaran, Dao, Dee N., Weinrick, Brian C., Vilchèze, Catherine, Gurcha, Sudagar S., Ojha, Anil, Kremer, Laurent, Besra, Gurdyal S., Hatfull, Graham F., Jacobs, William R.
Published 2013

ESX1-dependent fractalkine mediates chemotaxis and Mycobacterium tuberculosis infection in humans☆

by Hingley-Wilson, Suzanne M., Connell, David, Pollock, Katrina, Hsu, Tsungda, Tchilian, Elma, Sykes, Anny, Grass, Lisa, Potiphar, Lee, Bremang, Samuel, Kon, Onn Min, Jacobs, William R., Lalvani, Ajit
Published 2014

B Cells Regulate Neutrophilia during Mycobacterium tuberculosis Infection and BCG Vaccination by Modulating the Interleukin-17 Response

by Kozakiewicz, Lee, Chen, Yong, Xu, Jiayong, Wang, Yanhua, Dunussi-Joannopoulos, Kyri, Ou, Qinglin, Flynn, Joanne L., Porcelli, Steven A., Jacobs, William R., Chan, John
Published 2013

Specialized Transduction Designed for Precise High-Throughput Unmarked Deletions in Mycobacterium tuberculosis

by Jain, Paras, Hsu, Tsungda, Arai, Masayoshi, Biermann, Karolin, Thaler, David S., Nguyen, Andrew, González, Pablo A., Tufariello, Joann M., Kriakov, Jordan, Chen, Bing, Larsen, Michelle H., Jacobs, William R.
Published 2014

Increased TNF-α/IFN-γ/IL-2 and Decreased TNF-α/IFN-γ Production by Central Memory T Cells Are Associated with Protective Responses against Bovine Tuberculosis Following BCG Vaccina...

by Maggioli, Mayara F., Palmer, Mitchell V., Thacker, Tyler C., Vordermeier, Hans Martin, McGill, Jodi L., Whelan, Adam O., Larsen, Michelle H., Jacobs, William R., Waters, W. Ray
Published 2016

Metabolic Network for the Biosynthesis of Intra- and Extracellular α-Glucans Required for Virulence of Mycobacterium tuberculosis

by Koliwer-Brandl, Hendrik, Syson, Karl, van de Weerd, Robert, Chandra, Govind, Appelmelk, Ben, Alber, Marina, Ioerger, Thomas R., Jacobs, William R., Geurtsen, Jeroen, Bornemann, Stephen, Kalscheuer, Rainer
Published 2016