A 96-well DNase I footprinting screen for drug–DNA interactions

by Ellis, Tom, Evans, David A., Martin, Christopher R. H., Hartley, John A.
Published 2007

NF-Y activates genes of metabolic pathways altered in cancer cells

by Benatti, Paolo, Chiaramonte, Maria Luisa, Lorenzo, Mariangela, Hartley, John A., Hochhauser, Daniel, Gnesutta, Nerina, Mantovani, Roberto, Imbriano, Carol, Dolfini, Diletta
Published 2015

Role of Reactive Oxygen Species in the Abrogation of Oxaliplatin Activity by Cetuximab in Colorectal Cancer

by Santoro, Valeria, Jia, Ruochen, Thompson, Hannah, Nijhuis, Anke, Jeffery, Rosemary, Kiakos, Konstantinos, Silver, Andrew R., Hartley, John A., Hochhauser, Daniel
Published 2015

WASH and Tsg101/ALIX-dependent diversion of stress-internalized EGFR from the canonical endocytic pathway

by Tomas, Alejandra, Vaughan, Simon O., Burgoyne, Thomas, Sorkin, Alexander, Hartley, John A., Hochhauser, Daniel, Futter, Clare E.
Published 2015

The XPF-ERCC1 endonuclease and homologous recombination contribute to the repair of minor groove DNA interstrand crosslinks in mammalian cells produced by the pyrrolo[2,1-c][1,4]be...

by Clingen, Peter H., De Silva, Inusha U., McHugh, Peter J., Ghadessy, Farid J, Tilby, Michael J., Thurston, David E., Hartley, John A.
Published 2005

Characterization of the Human SNM1A and SNM1B/Apollo DNA Repair Exonucleases*

by Sengerová, Blanka, Allerston, Charles K., Abu, Mika, Lee, Sook Y., Hartley, Janet, Kiakos, Konstantinos, Schofield, Christopher J., Hartley, John A., Gileadi, Opher, McHugh, Peter J.
Published 2012

Evidence for different mechanisms of ‘unhooking’ for melphalan and cisplatin-induced DNA interstrand cross-links in vitro and in clinical acquired resistant tumour samples

by Spanswick, Victoria J, Lowe, Helen L, Newton, Claire, Bingham, John P, Bagnobianchi, Alessia, Kiakos, Konstantinos, Craddock, Charles, Ledermann, Jonathan A, Hochhauser, Daniel, Hartley, John A
Published 2012

Activity of the DNA minor groove cross-linking agent SG2000 (SJG-136) against canine tumours

by Mellinas-Gomez, Maria, Spanswick, Victoria J., Paredes-Moscosso, Solange R., Robson, Matthew, Pedley, R. Barbara, Thurston, David E., Baines, Stephen J., Stell, Anneliese, Hartley, John A.
Published 2015

Expression of somatostatin receptors 2 and 5 in circulating tumour cells from patients with neuroendocrine tumours

by Childs, Alexa, Vesely, Clare, Ensell, Leah, Lowe, Helen, Luong, Tu Vinh, Caplin, Martyn E, Toumpanakis, Christos, Thirlwell, Christina, Hartley, John A, Meyer, Tim
Published 2016

Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment

by Ip, Laura R. H., Poulogiannis, George, Viciano, Felipe Cia, Sasaki, Junko, Kofuji, Satoshi, Spanswick, Victoria J., Hochhauser, Daniel, Hartley, John A., Sasaki, Takehiko, Gewinner, Christina A.
Published 2015

Direct Involvement of Retinoblastoma Family Proteins in DNA Repair by Non-homologous End-Joining

by Cook, Rebecca, Zoumpoulidou, Georgia, Luczynski, Maciej T., Rieger, Simone, Moquet, Jayne, Spanswick, Victoria J., Hartley, John A., Rothkamm, Kai, Huang, Paul H., Mittnacht, Sibylle
Published 2015

A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer

by Ohnmacht, Stephan A, Marchetti, Chiara, Gunaratnam, Mekala, Besser, Rachael J, Haider, Shozeb M, Di Vita, Gloria, Lowe, Helen L, Mellinas-Gomez, Maria, Diocou, Seckou, Robson, Mathew, Šponer, Jiri, Islam, Barira, Barbara Pedley, R, Hartley, John A, Neidle, Stephen
Published 2015