Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

by Lu, Phoebe D., Harding, Heather P., Ron, David
Published 2004

Feedback Inhibition of the Unfolded Protein Response by GADD34-Mediated Dephosphorylation of eIF2α

by Novoa, Isabel, Zeng, Huiqing, Harding, Heather P., Ron, David
Published 2001

Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-γ

by Lin, Wensheng, Harding, Heather P., Ron, David, Popko, Brian
Published 2005

Uncoupling Proteostasis and Development in Vitro with a Small Molecule Inhibitor of the Pancreatic Endoplasmic Reticulum Kinase, PERK*

by Harding, Heather P., Zyryanova, Alisa F., Ron, David
Published 2012

Inhibition of a constitutive translation initiation factor 2α phosphatase, CReP, promotes survival of stressed cells

by Jousse, Céline, Oyadomari, Seiichi, Novoa, Isabel, Lu, Phoebe, Zhang, Yuhong, Harding, Heather P., Ron, David
Published 2003

Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK

by Marciniak, Stefan J., Garcia-Bonilla, Lidia, Hu, Junjie, Harding, Heather P., Ron, David
Published 2006

Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux

by Shang, Jie, Gao, Ningguo, Kaufman, Randal J., Ron, David, Harding, Heather P., Lehrman, Mark A.
Published 2007

Paradoxical Sensitivity to an Integrated Stress Response Blocking Mutation in Vanishing White Matter Cells

by Sekine, Yusuke, Zyryanova, Alisa, Crespillo-Casado, Ana, Amin-Wetzel, Niko, Harding, Heather P., Ron, David
Published 2016

Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants

by Tsunoda, Satoshi, Avezov, Edward, Zyryanova, Alisa, Konno, Tasuku, Mendes-Silva, Leonardo, Pinho Melo, Eduardo, Harding, Heather P, Ron, David
Published 2014

Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharides

by Gao, Ningguo, Shang, Jie, Huynh, Dang, Manthati, Vijaya L., Arias, Carolina, Harding, Heather P., Kaufman, Randal J., Mohr, Ian, Ron, David, Falck, John R., Lehrman, Mark A.
Published 2011

Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease

by Hori, Osamu, Ichinoda, Fusae, Tamatani, Takashi, Yamaguchi, Atsushi, Sato, Naoya, Ozawa, Kentaro, Kitao, Yasuko, Miyazaki, Mayuki, Harding, Heather P., Ron, David, Tohyama, Masaya, M Stern, David, Ogawa, Satoshi
Published 2002

Lifetime imaging of a fluorescent protein sensor reveals surprising stability of ER thiol redox

by Avezov, Edward, Cross, Benedict C.S., Kaminski Schierle, Gabriele S., Winters, Mikael, Harding, Heather P., Melo, Eduardo Pinho, Kaminski, Clemens F., Ron, David
Published 2013

Physiological modulation of BiP activity by trans-protomer engagement of the interdomain linker

by Preissler, Steffen, Chambers, Joseph E, Crespillo-Casado, Ana, Avezov, Edward, Miranda, Elena, Perez, Juan, Hendershot, Linda M, Harding, Heather P, Ron, David
Published 2015

G-actin provides substrate-specificity to eukaryotic initiation factor 2α holophosphatases

by Chen, Ruming, Rato, Cláudia, Yan, Yahui, Crespillo-Casado, Ana, Clarke, Hanna J, Harding, Heather P, Marciniak, Stefan J, Read, Randy J, Ron, David
Published 2015

Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum

by Avezov, Edward, Konno, Tasuku, Zyryanova, Alisa, Chen, Weiyue, Laine, Romain, Crespillo-Casado, Ana, Melo, Eduardo Pinho, Ushioda, Ryo, Nagata, Kazuhiro, Kaminski, Clemens F, Harding, Heather P, Ron, David
Published 2015

Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B

by Zyryanova, Alisa F., Weis, Félix, Faille, Alexandre, Abo Alard, Akeel, Crespillo-Casado, Ana, Sekine, Yusuke, Harding, Heather P., Allen, Felicity, Parts, Leopold, Fromont, Christoph, Fischer, Peter M., Warren, Alan J., Ron, David
Published 2018

Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress–Mitochondrial Dialog Triggering Lipotoxic Rodent and Human β-Cell Apoptosis

by Cunha, Daniel A., Igoillo-Esteve, Mariana, Gurzov, Esteban N., Germano, Carla M., Naamane, Najib, Marhfour, Ihsane, Fukaya, Makiko, Vanderwinden, Jean-Marie, Gysemans, Conny, Mathieu, Chantal, Marselli, Lorella, Marchetti, Piero, Harding, Heather P., Ron, David, Eizirik, Décio L., Cnop, Miriam
Published 2012

A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and Microcephaly

by Abdulkarim, Baroj, Nicolino, Marc, Igoillo-Esteve, Mariana, Daures, Mathilde, Romero, Sophie, Philippi, Anne, Senée, Valérie, Lopes, Miguel, Cunha, Daniel A., Harding, Heather P., Derbois, Céline, Bendelac, Nathalie, Hattersley, Andrew T., Eizirik, Décio L., Ron, David, Cnop, Miriam, Julier, Cécile
Published 2015

Skeletal muscle–specific eukaryotic translation initiation factor 2α phosphorylation controls amino acid metabolism and fibroblast growth factor 21–mediated non–cell-autonomous ene...

by Miyake, Masato, Nomura, Akitoshi, Ogura, Atsushi, Takehana, Kenji, Kitahara, Yoshihiro, Takahara, Kazuna, Tsugawa, Kazue, Miyamoto, Chinobu, Miura, Naoko, Sato, Ryosuke, Kurahashi, Kiyoe, Harding, Heather P., Oyadomari, Miho, Ron, David, Oyadomari, Seiichi
Published 2016