Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease

Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease

The rat homologue of a mitochondrial ATP-dependent protease Lon was cloned from cultured astrocytes exposed to hypoxia. Expression of Lon was enhanced in vitro by hypoxia or ER stress, and in vivo by brain ischemia. These observations suggested that changes in nuclear gene expression (Lon) triggered...

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Bibliographic Details
Main Authors: Hori, Osamu, Ichinoda, Fusae, Tamatani, Takashi, Yamaguchi, Atsushi, Sato, Naoya, Ozawa, Kentaro, Kitao, Yasuko, Miyazaki, Mayuki, Harding, Heather P., Ron, David, Tohyama, Masaya, M Stern, David, Ogawa, Satoshi
Format: Online
Language:English
Published: The Rockefeller University Press 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173558/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173558/

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