Modulation of 11β-Hydroxysteroid Dehydrogenase as a Strategy to Reduce Vascular Inflammation

by Hadoke, Patrick W. F., Kipari, Tiina, Seckl, Jonathan R., Chapman, Karen E.
Published 2013

11β-Hydroxysteroid dehydrogenase type 1 contributes to the regulation of 7-oxysterol levels in the arterial wall through the inter-conversion of 7-ketocholesterol and 7β-hydroxycho...

by Mitić, Tijana, Andrew, Ruth, Walker, Brian R., Hadoke, Patrick W.F.
Published 2013

Vascular Dysfunction in Horses with Endocrinopathic Laminitis

by Morgan, Ruth A., Keen, John A., Walker, Brian R., Hadoke, Patrick W. F.
Published 2016

Influence of Androgen Receptor in Vascular Cells on Reperfusion following Hindlimb Ischaemia

by Wu, Junxi, Hadoke, Patrick W. F., Takov, Kaloyan, Korczak, Agnieszka, Denvir, Martin A., Smith, Lee B.
Published 2016

Assessment of Spectral Doppler in Preclinical Ultrasound Using a Small-Size Rotating Phantom

by Yang, Xin, Sun, Chao, Anderson, Tom, Moran, Carmel M., Hadoke, Patrick W.F., Gray, Gillian A., Hoskins, Peter R.
Published 2013

Modulation of neointimal lesion formation by endogenous androgens is independent of vascular androgen receptor

by Wu, Junxi, Hadoke, Patrick W. F., Mair, Iris, Lim, Win Gel, Miller, Eileen, Denvir, Martin A., Smith, Lee B.
Published 2014

Regulation of angiogenesis through the efficient delivery of microRNAs into endothelial cells using polyamine-coated carbon nanotubes

by Masotti, Andrea, Miller, Mark R., Celluzzi, Antonella, Rose, Lorraine, Micciulla, Federico, Hadoke, Patrick W.F., Bellucci, Stefano, Caporali, Andrea
Published 2016

Haploinsufficiency of the murine Col3a1 locus causes aortic dissection: a novel model of the vascular type of Ehlers–Danlos syndrome

by Smith, Lee B., Hadoke, Patrick W.F., Dyer, Emma, Denvir, Martin A., Brownstein, David, Miller, Eileen, Nelson, Nancy, Wells, Sara, Cheeseman, Michael, Greenfield, Andy
Published 2011

Pulmonary diesel particulate increases susceptibility to myocardial ischemia/reperfusion injury via activation of sensory TRPV1 and β1 adrenoreceptors

by Robertson, Sarah, Thomson, Ashleigh L, Carter, Rod, Stott, Holly R, Shaw, Catherine A, Hadoke, Patrick W F, Newby, David E, Miller, Mark R, Gray, Gillian A
Published 2014

11β-Hydroxysteroid dehydrogenase type 1 contributes to the balance between 7-keto- and 7-hydroxy-oxysterols in vivo

by Mitić, Tijana, Shave, Steven, Semjonous, Nina, McNae, Iain, Cobice, Diego F., Lavery, Gareth G., Webster, Scott P., Hadoke, Patrick W.F., Walker, Brian R., Andrew, Ruth
Published 2013

Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography

by Kirkby, Nicholas S., Low, Lucinda, Wu, Junxi, Miller, Eileen, Seckl, Jonathan R., Walker, Brian R., Webb, David J., Hadoke, Patrick W. F.
Published 2015

Platelet activation independent of pulmonary inflammation contributes to diesel exhaust particulate-induced promotion of arterial thrombosis

by Tabor, Caroline M., Shaw, Catherine A., Robertson, Sarah, Miller, Mark R., Duffin, Rodger, Donaldson, Ken, Newby, David E., Hadoke, Patrick W. F.
Published 2016

Ablation of the androgen receptor from vascular smooth muscle cells demonstrates a role for testosterone in vascular calcification

by Zhu, Dongxing, Hadoke, Patrick W. F., Wu, Junxi, Vesey, Alex T., Lerman, Daniel. A., Dweck, Marc R., Newby, David E., Smith, Lee B., MacRae, Vicky E.
Published 2016

Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice*

by Michailidou, Zoi, Turban, Sophie, Miller, Eileen, Zou, Xiantong, Schrader, Joerg, Ratcliffe, Peter J., Hadoke, Patrick W. F., Walker, Brian R., Iredale, John P., Morton, Nicholas M., Seckl, Jonathan R.
Published 2012

A Stratified Transcriptomics Analysis of Polygenic Fat and Lean Mouse Adipose Tissues Identifies Novel Candidate Obesity Genes

by Morton, Nicholas M., Nelson, Yvonne B., Michailidou, Zoi, Di Rollo, Emma M., Ramage, Lynne, Hadoke, Patrick W. F., Seckl, Jonathan R., Bunger, Lutz, Horvat, Simon, Kenyon, Christopher J., Dunbar, Donald R.
Published 2011

Sertoli Cells Modulate Testicular Vascular Network Development, Structure, and Function to Influence Circulating Testosterone Concentrations in Adult Male Mice

by Rebourcet, Diane, Wu, Junxi, Cruickshanks, Lyndsey, Smith, Sarah E., Milne, Laura, Fernando, Anuruddika, Wallace, Robert J., Gray, Calum D., Hadoke, Patrick W. F., Mitchell, Rod T., O'Shaughnessy, Peter J., Smith, Lee B.
Published 2016

Combustion-derived nanoparticulate induces the adverse vascular effects of diesel exhaust inhalation

by Mills, Nicholas L., Miller, Mark R., Lucking, Andrew J., Beveridge, Jon, Flint, Laura, Boere, A. John F., Fokkens, Paul H., Boon, Nicholas A., Sandstrom, Thomas, Blomberg, Anders, Duffin, Rodger, Donaldson, Ken, Hadoke, Patrick W.F., Cassee, Flemming R., Newby, David E.
Published 2011

11β-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosis

by Kipari, Tiina, Hadoke, Patrick W. F., Iqbal, Javaid, Man, Tak-Yung, Miller, Eileen, Coutinho, Agnes E., Zhang, Zhenguang, Sullivan, Katie M., Mitic, Tijana, Livingstone, Dawn E. W., Schrecker, Christopher, Samuel, Kay, White, Christopher I., Bouhlel, M. Amine, Chinetti-Gbaguidi, Giulia, Staels, Bart, Andrew, Ruth, Walker, Brian R., Savill, John S., Chapman, Karen E., Seckl, Jonathan R.
Published 2013