Tissue-specific and convergent metabolic transformation of cancer correlates with metastatic potential and patient survival

by Gaude, Edoardo, Frezza, Christian
Published 2016

Defects in mitochondrial metabolism and cancer

by Gaude, Edoardo, Frezza, Christian
Published 2014

The stem cell secretome and its role in brain repair

by Drago, Denise, Cossetti, Chiara, Iraci, Nunzio, Gaude, Edoardo, Musco, Giovanna, Bachi, Angela, Pluchino, Stefano
Published 2013

Mutant Kras copy number defines metabolic reprogramming and therapeutic susceptibilities

by Kerr, Emma, Gaude, Edoardo, Turrell, Frances, Frezza, Christian, Martins, Carla P
Published 2016

Metabolic Reprograming of Mononuclear Phagocytes in Progressive Multiple Sclerosis

by Tannahill, Gillian Margaret, Iraci, Nunzio, Gaude, Edoardo, Frezza, Christian, Pluchino, Stefano
Published 2015

Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death

by Catanzaro, Daniela, Gaude, Edoardo, Orso, Genny, Giordano, Carla, Guzzo, Giulia, Rasola, Andrea, Ragazzi, Eugenio, Caparrotta, Laura, Frezza, Christian, Montopoli, Monica
Published 2015

Metabolic determinants of the immune modulatory function of neural stem cells

by Drago, Denise, Basso, Veronica, Gaude, Edoardo, Volpe, Giulio, Peruzzotti-Jametti, Luca, Bachi, Angela, Musco, Giovanna, Andolfo, Annapaola, Frezza, Christian, Mondino, Anna, Pluchino, Stefano
Published 2016

Hypoxia-induced nitric oxide production and tumour perfusion is inhibited by pegylated arginine deiminase (ADI-PEG20)

by Burrows, Natalie, Cane, Gaelle, Robson, Mathew, Gaude, Edoardo, J. Howat, William, Szlosarek, Peter W., Pedley, R. Barbara, Frezza, Christian, Ashcroft, Margaret, Maxwell, Patrick H.
Published 2016

Phenotype-based cell-specific metabolic modeling reveals metabolic liabilities of cancer

by Yizhak, Keren, Gaude, Edoardo, Le Dévédec, Sylvia, Waldman, Yedael Y, Stein, Gideon Y, van de Water, Bob, Frezza, Christian, Ruppin, Eytan
Published 2014

Near-complete elimination of mutant mtDNA by iterative or dynamic dose-controlled treatment with mtZFNs

by Gammage, Payam A., Gaude, Edoardo, Van Haute, Lindsey, Rebelo-Guiomar, Pedro, Jackson, Christopher B., Rorbach, Joanna, Pekalski, Marcin L., Robinson, Alan J., Charpentier, Marine, Concordet, Jean-Paul, Frezza, Christian, Minczuk, Michal
Published 2016

Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition

by Sciacovelli, Marco, Gonçalves, Emanuel, Isaac Johnson, Timothy, Roberto Zecchini, Vincent, da Costa, Ana Sofia Henriques, Gaude, Edoardo, Vercauteren Drubbel, Alizee, Julian Theobald, Sebastian, Abbo, Sandra, Tran, Maxine, Rajeeve, Vinothini, Cardaci, Simone, Foster, Sarah, Yun, Haiyang, Cutillas, Pedro, Warren, Anne, Gnanapragasam, Vincent, Gottlieb, Eyal, Franze, Kristian, Huntly, Brian, Richard Maher, Eamonn, Henry Maxwell, Patrick, Saez-Rodriguez, Julio, Frezza, Christian
Published 2016

Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer

by Zecchini, Vincent, Madhu, Basetti, Russell, Roslin, Pértega-Gomes, Nelma, Warren, Anne, Gaude, Edoardo, Borlido, Joana, Stark, Rory, Ireland-Zecchini, Heather, Rao, Roheet, Scott, Helen, Boren, Joan, Massie, Charlie, Asim, Mohammad, Brindle, Kevin, Griffiths, John, Frezza, Christian, Neal, David E, Mills, Ian G
Published 2014

Fumarate induces redox-dependent senescence by modifying glutathione metabolism

by Zheng, Liang, Cardaci, Simone, Jerby, Livnat, MacKenzie, Elaine D., Sciacovelli, Marco, Johnson, T. Isaac, Gaude, Edoardo, King, Ayala, Leach, Joshua D. G., Edrada-Ebel, RuAngelie, Hedley, Ann, Morrice, Nicholas A., Kalna, Gabriela, Blyth, Karen, Ruppin, Eytan, Frezza, Christian, Gottlieb, Eyal
Published 2015

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

by Chouchani, Edward T., Pell, Victoria R., Gaude, Edoardo, Aksentijević, Dunja, Sundier, Stephanie Y., Robb, Ellen L., Logan, Angela, Nadtochiy, Sergiy M., Ord, Emily N. J., Smith, Anthony C., Eyassu, Filmon, Shirley, Rachel, Hu, Chou-Hui, Dare, Anna J., James, Andrew M., Rogatti, Sebastian, Hartley, Richard C., Eaton, Simon, Costa, Ana S.H., Brookes, Paul S., Davidson, Sean M., Duchen, Michael R., Saeb-Parsy, Kourosh, Shattock, Michael J., Robinson, Alan J., Work, Lorraine M., Frezza, Christian, Krieg, Thomas, Murphy, Michael P.
Published 2014