Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death

Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death

The mechanisms of cisplatin resistance, one of the major limitations of current chemotherapy, has only partially been described. We previously demonstrated that cisplatin-resistant ovarian cancer cells (C13), are characterized by reduced mitochondrial activity and higher glucose-dependency when comp...

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Bibliographic Details
Main Authors: Catanzaro, Daniela, Gaude, Edoardo, Orso, Genny, Giordano, Carla, Guzzo, Giulia, Rasola, Andrea, Ragazzi, Eugenio, Caparrotta, Laura, Frezza, Christian, Montopoli, Monica
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745784/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745784/

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