Genetics and genomics of Parkinson’s disease

by Lin, Michelle K, Farrer, Matthew J
Published 2014

Leucine-rich repeat kinase 2 (LRRK2) regulates α-synuclein clearance in microglia

by Maekawa, Tatsunori, Sasaoka, Toshikuni, Azuma, Sadahiro, Ichikawa, Takafumi, Melrose, Heather L., Farrer, Matthew J., Obata, Fumiya
Published 2016

Measuring dopaminergic function in the 6-OHDA-lesioned rat: a comparison of PET and microdialysis

by Walker, Matthew D, Dinelle, Katherine, Kornelsen, Rick, Lee, Anna, Farrer, Matthew J, Stoessl, A Jon, Sossi, Vesna
Published 2013

LRRK2 phosphorylates novel tau epitopes and promotes tauopathy

by Bailey, Rachel M., Covy, Jason P., Melrose, Heather L., Rousseau, Linda, Watkinson, Ruth, Knight, Joshua, Miles, Sarah, Farrer, Matthew J., Dickson, Dennis W., Giasson, Benoit I., Lewis, Jada
Published 2013

Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice

by Beccano-Kelly, Dayne A., Kuhlmann, Naila, Tatarnikov, Igor, Volta, Mattia, Munsie, Lise N., Chou, Patrick, Cao, Li-Ping, Han, Heather, Tapia, Lucia, Farrer, Matthew J., Milnerwood, Austen J.
Published 2014

Polymorphic genes of detoxification and mitochondrial enzymes and risk for progressive supranuclear palsy: a case control study

by Potts, Lisa F, Cambon, Alex C, Ross, Owen A, Rademakers, Rosa, Dickson, Dennis W, Uitti, Ryan J, Wszolek, Zbigniew K, Rai, Shesh N, Farrer, Matthew J, Hein, David W, Litvan, Irene
Published 2012

LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors

by Hinkle, Kelly M, Yue, Mei, Behrouz, Bahareh, Dächsel, Justus C, Lincoln, Sarah J, Bowles, Erin E, Beevers, Joel E, Dugger, Brittany, Winner, Beate, Prots, Iryna, Kent, Caroline B, Nishioka, Kenya, Lin, Wen-Lang, Dickson, Dennis W, Janus, Christopher J, Farrer, Matthew J, Melrose, Heather L
Published 2012

De novo FGF12 mutation in 2 patients with neonatal-onset epilepsy

by Guella, Ilaria, Huh, Linda, McKenzie, Marna B., Toyota, Eric B., Bebin, E. Martina, Thompson, Michelle L., Cooper, Gregory M., Evans, Daniel M., Buerki, Sarah E., Adam, Shelin, Van Allen, Margot I., Nelson, Tanya N., Connolly, Mary B., Farrer, Matthew J., Demos, Michelle
Published 2016

Identification of common variants influencing risk of the tauopathy Progressive Supranuclear Palsy

by Höglinger, Günter U., Melhem, Nadine M., Dickson, Dennis W., Sleiman, Patrick M.A., Wang, Li-San, Klei, Lambertus, Rademakers, Rosa, de Silva, Rohan, Litvan, Irene, Riley, David E., van Swieten, John C., Heutink, Peter, Wszolek, Zbigniew K., Uitti, Ryan J., Vandrovcova, Jana, Hurtig, Howard I., Gross, Rachel G., Maetzler, Walter, Goldwurm, Stefano, Tolosa, Eduardo, Borroni, Barbara, Pastor, Pau, Cantwell, Laura B., Han, Mi Ryung, Dillman, Allissa, van der Brug, Marcel P., Gibbs, J Raphael, Cookson, Mark R., Hernandez, Dena G., Singleton, Andrew B., Farrer, Matthew J., Yu, Chang-En, Golbe, Lawrence I., Revesz, Tamas, Hardy, John, Lees, Andrew J., Devlin, Bernie, Hakonarson, Hakon, Müller, Ulrich, Schellenberg, Gerard D.
Published 2011

Correction: Genome-Wide Association Study Identifies Novel Restless Legs Syndrome Susceptibility Loci on 2p14 and 16q12.1

by Winkelmann, Juliane, Czamara, Darina, Schormair, Barbara, Knauf, Franziska, Schulte, Eva C., Trenkwalder, Claudia, Dauvilliers, Yves, Polo, Olli, Högl, Birgit, Berger, Klaus, Fuhs, Andrea, Gross, Nadine, Stiasny-Kolster, Karin, Oertel, Wolfgang, Bachmann, Cornelius G., Paulus, Walter, Xiong, Lan, Montplaisir, Jacques, Rouleau, Guy A., Fietze, Ingo, Vávrová, Jana, Kemlink, David, Sonka, Karel, Nevsimalova, Sona, Lin, Siong-Chi, Wszolek, Zbigniew, Vilariño-Güell, Carles, Farrer, Matthew J., Gschliesser, Viola, Frauscher, Birgit, Falkenstetter, Tina, Poewe, Werner, Allen, Richard P., Earley, Christopher J., Ondo, William G., Le, Wei-Dong, Spieler, Derek, Kaffe, Maria, Zimprich, Alexander, Kettunen, Johannes, Perola, Markus, Silander, Kaisa, Cournu-Rebeix, Isabelle, Francavilla, Marcella, Fontenille, Claire, Fontaine, Bertrand, Vodicka, Pavel, Prokisch, Holger, Lichtner, Peter, Peppard, Paul, Faraco, Juliette, Mignot, Emmanuel, Gieger, Christian, Illig, Thomas, Wichmann, H.-Erich, Müller-Myhsok, Bertram, Meitinger, Thomas
Published 2011

Genome-Wide Association Study Identifies Novel Restless Legs Syndrome Susceptibility Loci on 2p14 and 16q12.1

by Winkelmann, Juliane, Czamara, Darina, Schormair, Barbara, Knauf, Franziska, Schulte, Eva C., Trenkwalder, Claudia, Dauvilliers, Yves, Polo, Olli, Högl, Birgit, Berger, Klaus, Fuhs, Andrea, Gross, Nadine, Stiasny-Kolster, Karin, Oertel, Wolfgang, Bachmann, Cornelius G., Paulus, Walter, Xiong, Lan, Montplaisir, Jacques, Rouleau, Guy A., Fietze, Ingo, Vávrová, Jana, Kemlink, David, Sonka, Karel, Nevsimalova, Sona, Lin, Siong-Chi, Wszolek, Zbigniew, Vilariño-Güell, Carles, Farrer, Matthew J., Gschliesser, Viola, Frauscher, Birgit, Falkenstetter, Tina, Poewe, Werner, Allen, Richard P., Earley, Christopher J., Ondo, William G., Le, Wei-Dong, Spieler, Derek, Kaffe, Maria, Zimprich, Alexander, Kettunen, Johannes, Perola, Markus, Silander, Kaisa, Cournu-Rebeix, Isabelle, Francavilla, Marcella, Fontenille, Claire, Fontaine, Bertrand, Vodicka, Pavel, Prokisch, Holger, Lichtner, Peter, Peppard, Paul, Faraco, Juliette, Mignot, Emmanuel, Gieger, Christian, Illig, Thomas, Wichmann, H.-Erich, Müller-Myhsok, Bertram, Meitinger, Thomas
Published 2011

Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database

by Lill, Christina M., Roehr, Johannes T., McQueen, Matthew B., Kavvoura, Fotini K., Bagade, Sachin, Schjeide, Brit-Maren M., Schjeide, Leif M., Meissner, Esther, Zauft, Ute, Allen, Nicole C., Liu, Tian, Schilling, Marcel, Anderson, Kari J., Beecham, Gary, Berg, Daniela, Biernacka, Joanna M., Brice, Alexis, DeStefano, Anita L., Do, Chuong B., Eriksson, Nicholas, Factor, Stewart A., Farrer, Matthew J., Foroud, Tatiana, Gasser, Thomas, Hamza, Taye, Hardy, John A., Heutink, Peter, Hill-Burns, Erin M., Klein, Christine, Latourelle, Jeanne C., Maraganore, Demetrius M., Martin, Eden R., Martinez, Maria, Myers, Richard H., Nalls, Michael A., Pankratz, Nathan, Payami, Haydeh, Satake, Wataru, Scott, William K., Sharma, Manu, Singleton, Andrew B., Stefansson, Kari, Toda, Tatsushi, Tung, Joyce Y., Vance, Jeffery, Wood, Nick W., Zabetian, Cyrus P., Young, Peter, Tanzi, Rudolph E., Khoury, Muin J., Zipp, Frauke, Lehrach, Hans, Ioannidis, John P. A., Bertram, Lars
Published 2012