Molecules That Cause or Prevent Parkinson's Disease

by Cookson, Mark R
Published 2004

Evolutionary and functional relationships within the DJ1 superfamily

by Bandyopadhyay, Sourav, Cookson, Mark R
Published 2004

Gene expression in the Parkinson's disease brain

by Lewis, Patrick A., Cookson, Mark R.
Published 2012

LRRK2 at the interface of autophagosomes, endosomes and lysosomes

by Roosen, Dorien A., Cookson, Mark R.
Published 2016

Is inhibition of kinase activity the only therapeutic strategy for LRRK2-associated Parkinson's disease?

by Rudenko, Iakov N, Chia, Ruth, Cookson, Mark R
Published 2012

Cell population-specific expression analysis of human cerebellum

by Kuhn, Alexandre, Kumar, Azad, Beilina, Alexandra, Dillman, Allissa, Cookson, Mark R, Singleton, Andrew B
Published 2012

Post-Translational Decrease in Respiratory Chain Proteins in the Polg Mutator Mouse Brain

by Hauser, David N., Dillman, Allissa A., Ding, Jinhui, Li, Yan, Cookson, Mark R.
Published 2014

The Polg Mutator Phenotype Does Not Cause Dopaminergic Neurodegeneration in DJ-1-Deficient Mice1,2,3

by Hauser, David N., Primiani, Christopher T., Langston, Rebekah G., Kumaran, Ravindran, Cookson, Mark R.
Published 2015

LRRK2 Kinase Activity Is Dependent on LRRK2 GTP Binding Capacity but Independent of LRRK2 GTP Binding

by Taymans, Jean-Marc, Vancraenenbroeck, Renée, Ollikainen, Petri, Beilina, Alexandra, Lobbestael, Evy, De Maeyer, Marc, Baekelandt, Veerle, Cookson, Mark R.
Published 2011

Arsenite Stress Down-regulates Phosphorylation and 14-3-3 Binding of Leucine-rich Repeat Kinase 2 (LRRK2), Promoting Self-association and Cellular Redistribution*

by Mamais, Adamantios, Chia, Ruth, Beilina, Alexandra, Hauser, David N., Hall, Christine, Lewis, Patrick A., Cookson, Mark R., Bandopadhyay, Rina
Published 2014

Identification of Stk25 as a Genetic Modifier of Tau Phosphorylation in Dab1-Mutant Mice

by Matsuki, Tohru, Zaka, Mariam, Guerreiro, Rita, van der Brug, Marcel P., Cooper, Jonathan A., Cookson, Mark R., Hardy, John A., Howell, Brian W.
Published 2012

Messenger RNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex

by Dillman, Allissa A., Hauser, David N., Gibbs, J. Raphael, Nalls, Michael A., McCoy, Melissa K., Rudenko, Iakov N., Galter, Dagmar, Cookson, Mark R.
Published 2013

Age-associated miRNA Alterations in Skeletal Muscle from Rhesus Monkeys reversed by caloric restriction

by Mercken, Evi M., Majounie, Elisa, Ding, Jinhui, Guo, Rong, Kim, Jiyoung, Bernier, Michel, Mattison, Julie, Cookson, Mark R., Gorospe, Myriam, de Cabo, Rafael, Abdelmohsen, Kotb
Published 2013

Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7

by Chia, Ruth, Haddock, Sara, Beilina, Alexandra, Rudenko, Iakov N, Mamais, Adamantios, Kaganovich, Alice, Li, Yan, Kumaran, Ravindran, Nalls, Michael A, Cookson, Mark R
Published 2014

Biochemical Characterization of Highly Purified Leucine-Rich Repeat Kinases 1 and 2 Demonstrates Formation of Homodimers

by Civiero, Laura, Vancraenenbroeck, Renée, Belluzzi, Elisa, Beilina, Alexandra, Lobbestael, Evy, Reyniers, Lauran, Gao, Fangye, Micetic, Ivan, De Maeyer, Marc, Bubacco, Luigi, Baekelandt, Veerle, Cookson, Mark R., Greggio, Elisa, Taymans, Jean-Marc
Published 2012

Resolving the polymorphism-in-probe problem is critical for correct interpretation of expression QTL studies

by Ramasamy, Adaikalavan, Trabzuni, Daniah, Gibbs, J. Raphael, Dillman, Allissa, Hernandez, Dena G., Arepalli, Sampath, Walker, Robert, Smith, Colin, Ilori, Gigaloluwa Peter, Shabalin, Andrey A., Li, Yun, Singleton, Andrew B., Cookson, Mark R., Hardy, John, Ryten, Mina, Weale, Michael E.
Published 2013

mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1

by Manzoni, Claudia, Mamais, Adamantios, Roosen, Dorien A., Dihanich, Sybille, Soutar, Marc P. M., Plun-Favreau, Helene, Bandopadhyay, Rina, Hardy, John, Tooze, Sharon A., Cookson, Mark R., Lewis, Patrick A.
Published 2016

Comprehensive promoter level expression quantitative trait loci analysis of the human frontal lobe

by Blauwendraat, Cornelis, Francescatto, Margherita, Gibbs, J. Raphael, Jansen, Iris E., Simón-Sánchez, Javier, Hernandez, Dena G., Dillman, Allissa A., Singleton, Andrew B., Cookson, Mark R., Rizzu, Patrizia, Heutink, Peter
Published 2016

Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue

by Devine, Michael J., Kaganovich, Alice, Ryten, Mina, Mamais, Adamantios, Trabzuni, Daniah, Manzoni, Claudia, McGoldrick, Philip, Chan, Diane, Dillman, Allissa, Zerle, Julia, Horan, Susannah, Taanman, Jan-Willem, Hardy, John, Marti-Masso, Jose-Felix, Healey, Daniel, Schapira, Anthony H., Wolozin, Benjamin, Bandopadhyay, Rina, Cookson, Mark R., van der Brug, Marcel P., Lewis, Patrick A.
Published 2011

Deletion at ITPR1 Underlies Ataxia in Mice and Spinocerebellar Ataxia 15 in Humans

by van de Leemput, Joyce, Chandran, Jayanth, Knight, Melanie A, Holtzclaw, Lynne A, Scholz, Sonja, Cookson, Mark R, Houlden, Henry, Gwinn-Hardy, Katrina, Fung, Hon-Chung, Lin, Xian, Hernandez, Dena, Simon-Sanchez, Javier, Wood, Nick W, Giunti, Paola, Rafferty, Ian, Hardy, John, Storey, Elsdon, Gardner, R. J. McKinlay, Forrest, Susan M, Fisher, Elizabeth M. C, Russell, James T, Cai, Huaibin, Singleton, Andrew B
Published 2007