Crystal Structure of the FERM-SH2 Module of Human Jak2

by McNally, Randall, Toms, Angela V., Eck, Michael J.
Published 2016

Crystal Structure of a Coiled-Coil Domain from Human ROCK I

by Tu, Daqi, Li, Yiqun, Song, Hyun Kyu, Toms, Angela V., Gould, Christopher J., Ficarro, Scott B., Marto, Jarrod A., Goode, Bruce L., Eck, Michael J.
Published 2011

Structure of a pseudokinase domain switch that controls oncogenic activation of Jak kinases

by Toms, Angela V., Deshpande, Anagha, McNally, Randall, Jeong, Youngjee, Rogers, Julia M., Kim, Chae Un, Gruner, Sol M., Ficarro, Scott B., Marto, Jarrod A., Sattler, Martin, Griffin, James D., Eck, Michael J.
Published 2013

MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells

by Wang, Yubao, Lee, Young-Mi, Baitsch, Lukas, Huang, Alan, Xiang, Yi, Tong, Haoxuan, Lako, Ana, Von, Thanh, Choi, Christine, Lim, Elgene, Min, Junxia, Li, Li, Stegmeier, Frank, Schlegel, Robert, Eck, Michael J, Gray, Nathanael S, Mitchison, Timothy J, Zhao, Jean J
Published 2014

Structure and mechanism of activity-based inhibition of the EGF-Receptor by Mig6

by Park, Eunyoung, Kim, Nayoung, Ficarro, Scott B., Zhang, Yi, Lee, Byung Il, Cho, Ahye, Kim, Kihong, Park, Angela K.J., Park, Woong-Yang, Murray, Bradley, Meyerson, Matthew, Beroukhim, Rameen, Marto, Jarrod A., Cho, Jeonghee, Eck, Michael J.
Published 2015

Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab

by Cho, Jeonghee, Bass, Adam J, Lawrence, Michael S, Cibulskis, Kristian, Cho, Ahye, Lee, Shi-Nai, Yamauchi, Mai, Wagle, Nikhil, Pochanard, Panisa, Kim, Nayoung, Park, Angela KJ, Won, Jonghwa, Hur, Hyung-Suk, Greulich, Heidi, Ogino, Shuji, Sougnez, Carrie, Voet, Douglas, Tabernero, Josep, Jimenez, Jose, Baselga, Jose, Gabriel, Stacey B, Lander, Eric S, Getz, Gad, Eck, Michael J, Park, Woong-Yang, Meyerson, Matthew
Published 2014

Overcoming EGFR T790M and C797S resistance with mutant-selective allosteric inhibitors

by Jia, Yong, Yun, Cai-Hong, Park, Eunyoung, Ercan, Dalia, Manuia, Mari, Juarez, Jose, Xu, Chunxiao, Rhee, Kevin, Chen, Ting, Zhang, Haikuo, Palakurthi, Sangeetha, Jang, Jaebong, Lelais, Gerald, DiDonato, Michael, Bursulaya, Badry, Michellys, Pierre-Yves, Epple, Robert, Marsilje, Thomas H., McNeill, Matthew, Lu, Wenshuo, Harris, Jennifer, Bender, Steven, Wong, Kwok-Kin, Jänne, Pasi A., Eck, Michael J.
Published 2016

Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition

by Weigert, Oliver, Lane, Andrew A., Bird, Liat, Kopp, Nadja, Chapuy, Bjoern, van Bodegom, Diederik, Toms, Angela V., Marubayashi, Sachie, Christie, Amanda L., McKeown, Michael, Paranal, Ronald M., Bradner, James E., Yoda, Akinori, Gaul, Christoph, Vangrevelinghe, Eric, Romanet, Vincent, Murakami, Masato, Tiedt, Ralph, Ebel, Nicolas, Evrot, Emeline, De Pover, Alain, Régnier, Catherine H., Erdmann, Dirk, Hofmann, Francesco, Eck, Michael J., Sallan, Stephen E., Levine, Ross L., Kung, Andrew L., Baffert, Fabienne, Radimerski, Thomas, Weinstock, David M.
Published 2012

Data publication with the structural biology data grid supports live analysis

by Meyer, Peter A., Socias, Stephanie, Key, Jason, Ransey, Elizabeth, Tjon, Emily C., Buschiazzo, Alejandro, Lei, Ming, Botka, Chris, Withrow, James, Neau, David, Rajashankar, Kanagalaghatta, Anderson, Karen S., Baxter, Richard H., Blacklow, Stephen C., Boggon, Titus J., Bonvin, Alexandre M. J. J., Borek, Dominika, Brett, Tom J., Caflisch, Amedeo, Chang, Chung-I, Chazin, Walter J., Corbett, Kevin D., Cosgrove, Michael S., Crosson, Sean, Dhe-Paganon, Sirano, Di Cera, Enrico, Drennan, Catherine L., Eck, Michael J., Eichman, Brandt F., Fan, Qing R., Ferré-D'Amaré, Adrian R., Christopher Fromme, J., Garcia, K. Christopher, Gaudet, Rachelle, Gong, Peng, Harrison, Stephen C., Heldwein, Ekaterina E., Jia, Zongchao, Keenan, Robert J., Kruse, Andrew C., Kvansakul, Marc, McLellan, Jason S., Modis, Yorgo, Nam, Yunsun, Otwinowski, Zbyszek, Pai, Emil F., Pereira, Pedro José Barbosa, Petosa, Carlo, Raman, C. S., Rapoport, Tom A., Roll-Mecak, Antonina, Rosen, Michael K., Rudenko, Gabby, Schlessinger, Joseph, Schwartz, Thomas U., Shamoo, Yousif, Sondermann, Holger, Tao, Yizhi J., Tolia, Niraj H., Tsodikov, Oleg V., Westover, Kenneth D., Wu, Hao, Foster, Ian, Fraser, James S., Maia, Filipe R. N C., Gonen, Tamir, Kirchhausen, Tom, Diederichs, Kay, Crosas, Mercè, Sliz, Piotr
Published 2016