Current and Potential Treatments for Ubiquitous but Neglected Herpesvirus Infections

by Gable, Jonathan E., Acker, Timothy M., Craik, Charles S.
Published 2014

Cullin E3 Ligases and Their Rewiring by Viral Factors

by Mahon, Cathal, Krogan, Nevan J., Craik, Charles S., Pick, Elah
Published 2014

Evolutionary Selection on Barrier Activity: Bar1 Is an Aspartyl Protease with Novel Substrate Specificity

by Jones, Stephen K., Clarke, Starlynn C., Craik, Charles S., Bennett, Richard J.
Published 2015

Sensitive and Selective Plasmon Ruler Nanosensors for Monitoring the Apoptotic Drug Response in Leukemia

by Tajon, Cheryl A., Seo, Daeha, Asmussen, Jennifer, Shah, Neil, Jun, Young-wook, Craik, Charles S.
Published 2014

Structure-Function Analyses of Human Kallikrein-related Peptidase 2 Establish the 99-Loop as Master Regulator of Activity*

by Skala, Wolfgang, Utzschneider, Daniel T., Magdolen, Viktor, Debela, Mekdes, Craik, Charles S., Brandstetter, Hans, Goettig, Peter
Published 2014

Cysteine and Aspartyl Proteases Contribute to Protein Digestion in the Gut of Freshwater Planaria

by Goupil, Louise S., Ivry, Sam L., Hsieh, Ivy, Suzuki, Brian M., Craik, Charles S., O’Donoghue, Anthony J., McKerrow, James H.
Published 2016

Clustering of disulfide-rich peptides provides scaffolds for hit discovery by phage display: application to interleukin-23

by Barkan, David T., Cheng, Xiao-li, Celino, Herodion, Tran, Tran T., Bhandari, Ashok, Craik, Charles S., Sali, Andrej, Smythe, Mark L.
Published 2016

Broad-Spectrum Allosteric Inhibition of Herpesvirus Proteases

by Gable, Jonathan E., Lee, Gregory M., Jaishankar, Priyadarshini, Hearn, Brian R., Waddling, Christopher A., Renslo, Adam R., Craik, Charles S.
Published 2014

Global Substrate Profiling of Proteases in Human Neutrophil Extracellular Traps Reveals Consensus Motif Predominantly Contributed by Elastase

by O’Donoghue, Anthony J., Jin, Ye, Knudsen, Giselle M., Perera, Natascha C., Jenne, Dieter E., Murphy, John E., Craik, Charles S., Hermiston, Terry W.
Published 2013

Imaging the Urokinase Plasminongen Activator Receptor in Preclinical Breast Cancer Models of Acquired Drug Resistance

by LeBeau, Aaron M., Sevillano, Natalia, King, Mandy L., Duriseti, Sai, Murphy, Stephanie T., Craik, Charles S., Murphy, Laura L., VanBrocklin, Henry F.
Published 2014

Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival and Virulence

by Clarke, Starlynn C., Dumesic, Phillip A., Homer, Christina M., O’Donoghue, Anthony J., La Greca, Florencia, Pallova, Lenka, Majer, Pavel, Madhani, Hiten D., Craik, Charles S.
Published 2016

Non-invasive imaging and cellular tracking of pulmonary emboli by near-infrared fluorescence and positron-emission tomography

by Page, Michael J., Lourenço, André L., David, Tovo, LeBeau, Aaron M., Cattaruzza, Fiore, Castro, Helena C., VanBrocklin, Henry F., Coughlin, Shaun R., Craik, Charles S.
Published 2015

GPS-Prot: A web-based visualization platform for integrating host-pathogen interaction data

by Fahey, Marie E, Bennett, Melanie J, Mahon, Cathal, Jäger, Stefanie, Pache, Lars, Kumar, Dhiraj, Shapiro, Alex, Rao, Kanury, Chanda, Sumit K, Craik, Charles S, Frankel, Alan D, Krogan, Nevan J
Published 2011

Investigation of the Proteolytic Functions of an Expanded Cercarial Elastase Gene Family in Schistosoma mansoni

by Ingram, Jessica R., Rafi, Salma B., Eroy-Reveles, A. Alegra, Ray, Manisha, Lambeth, Laura, Hsieh, Ivy, Ruelas, Debbie, Lim, K. C., Sakanari, Judy, Craik, Charles S., Jacobson, Matthew P., McKerrow, James H.
Published 2012

Dissecting the Active Site of the Collagenolytic Cathepsin L3 Protease of the Invasive Stage of Fasciola hepatica

by Corvo, Ileana, O'Donoghue, Anthony J., Pastro, Lucía, Pi-Denis, Natalia, Eroy-Reveles, Alegra, Roche, Leda, McKerrow, James H., Dalton, John P., Craik, Charles S., Caffrey, Conor R., Tort, José F.
Published 2013

Design of Selective Substrates and Activity-Based Probes for Hydrolase Important for Pathogenesis 1 (HIP1) from Mycobacterium tuberculosis

by Lentz, Christian S., Ordonez, Alvaro A., Kasperkiewicz, Paulina, La Greca, Florencia, O’Donoghue, Anthony J., Schulze, Christopher J., Powers, James C., Craik, Charles S., Drag, Marcin, Jain, Sanjay K., Bogyo, Matthew
Published 2016

Global Identification of Biofilm-Specific Proteolysis in Candida albicans

by Winter, Michael B., Salcedo, Eugenia C., Lohse, Matthew B., Hartooni, Nairi, Gulati, Megha, Sanchez, Hiram, Takagi, Julie, Hube, Bernhard, Andes, David R., Johnson, Alexander D., Craik, Charles S., Nobile, Clarissa J.
Published 2016

Structure and function based design of Plasmodium-selective proteasome inhibitors

by Li, Hao, O'Donoghue, Anthony J., van der Linden, Wouter A., Xie, Stanley C., Yoo, Euna, Foe, Ian T., Tilley, Leann, Craik, Charles S., da Fonseca, Paula C. A., Bogyo, Matthew
Published 2016