Cullin E3 Ligases and Their Rewiring by Viral Factors

The ability of viruses to subvert host pathways is central in disease pathogenesis. Over the past decade, a critical role for the Ubiquitin Proteasome System (UPS) in counteracting host immune factors during viral infection has emerged. This counteraction is commonly achieved by the expression of vi...

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Bibliographic Details
Main Authors: Mahon, Cathal, Krogan, Nevan J., Craik, Charles S., Pick, Elah
Format: Online
Language:English
Published: MDPI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279162/