A new era for small molecule screening: from new targets, such as JAK2 V617F, to complex cellular screens

by Constantinescu, Stefan N
Published 2009

The JAK-STAT pathway and hematopoietic stem cells from the JAK2 V617F perspective

by Staerk, Judith, Constantinescu, Stefan N.
Published 2012

Extracellular Domain N-Glycosylation Controls Human Thrombopoietin Receptor Cell Surface Levels

by Albu, Roxana I., Constantinescu, Stefan N.
Published 2011

Recent advances in understanding myelofibrosis and essential thrombocythemia

by Vainchenker, William, Constantinescu, Stefan N., Plo, Isabelle
Published 2016

Germline Counterparts of Oncogenic Mutations: Who Gives a JAK?

by Mead, Adam J., Constantinescu, Stefan N., Jacobsen, Sten Eirik W.
Published 2013

Neurobiology of Vascular Dementia

by Enciu, Ana-Maria, Constantinescu, Stefan N., Popescu, Laurenţiu M., Mureşanu, Dafin F., Popescu, Bogdan O.
Published 2011

Therapy targets in glioblastoma and cancer stem cells: lessons from haematopoietic neoplasms

by Cruceru, Maria Linda, Neagu, Monica, Demoulin, Jean-Baptiste, Constantinescu, Stefan N
Published 2013

Signal transduction molecule patterns indicating potential glioblastoma therapy approaches

by Cruceru, Maria Linda, Enciu, Ana-Maria, Popa, Adrian Claudiu, Albulescu, Radu, Neagu, Monica, Tanase, Cristiana Pistol, Constantinescu, Stefan N
Published 2013

Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Aβ Oligomers in Cells

by Decock, Marie, Stanga, Serena, Octave, Jean-Noël, Dewachter, Ilse, Smith, Steven O., Constantinescu, Stefan N., Kienlen-Campard, Pascal
Published 2016

Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing

by Decock, Marie, El Haylani, Laetitia, Stanga, Serena, Dewachter, Ilse, Octave, Jean-Noël, Smith, Steven O., Constantinescu, Stefan N., Kienlen-Campard, Pascal
Published 2015

Uncoupling JAK2 V617F activation from cytokine-induced signalling by modulation of JH2 αC helix

by Leroy, Emilie, Dusa, Alexandra, Colau, Didier, Motamedi, Amir, Cahu, Xavier, Mouton, Céline, Huang, Lily J., Shiau, Andrew K., Constantinescu, Stefan N.
Published 2016

An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia

by Plo, Isabelle, Zhang, Yanyan, Le Couédic, Jean-Pierre, Nakatake, Mayuka, Boulet, Jean-Michel, Itaya, Miki, Smith, Steven O., Debili, Najet, Constantinescu, Stefan N., Vainchenker, William, Louache, Fawzia, de Botton, Stéphane
Published 2009

Combination treatment for myeloproliferative neoplasms using JAK and pan-class I PI3K inhibitors

by Choong, Meng Ling, Pecquet, Christian, Pendharkar, Vishal, Diaconu, Carmen C, Yong, Jacklyn Wei Yan, Tai, Shi Jing, Wang, Si Fang, Defour, Jean-Philippe, Sangthongpitag, Kanda, Villeval, Jean-Luc, Vainchenker, William, Constantinescu, Stefan N, Lee, May Ann
Published 2013

FLT3-ITDs Instruct a Myeloid Differentiation and Transformation Bias in Lymphomyeloid Multipotent Progenitors

by Mead, Adam J., Kharazi, Shabnam, Atkinson, Deborah, Macaulay, Iain, Pecquet, Christian, Loughran, Stephen, Lutteropp, Michael, Woll, Petter, Chowdhury, Onima, Luc, Sidinh, Buza-Vidas, Natalija, Ferry, Helen, Clark, Sally-Ann, Goardon, Nicolas, Vyas, Paresh, Constantinescu, Stefan N., Sitnicka, Ewa, Nerlov, Claus, Jacobsen, Sten Eirik W.
Published 2013