Epigenetic Induction of EGR-1 Expression by the Amyloid Precursor Protein during Exposure to Novelty

by Hendrickx, Aurélie, Pierrot, Nathalie, Tasiaux, Bernadette, Schakman, Olivier, Brion, Jean-Pierre, Kienlen-Campard, Pascal, De Smet, Charles, Octave, Jean-Noël
Published 2013

Epigenetic Regulations of Immediate Early Genes Expression Involved in Memory Formation by the Amyloid Precursor Protein of Alzheimer Disease

by Hendrickx, Aurélie, Pierrot, Nathalie, Tasiaux, Bernadette, Schakman, Olivier, Kienlen-Campard, Pascal, De Smet, Charles, Octave, Jean-Noël
Published 2014

Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Aβ Oligomers in Cells

by Decock, Marie, Stanga, Serena, Octave, Jean-Noël, Dewachter, Ilse, Smith, Steven O., Constantinescu, Stefan N., Kienlen-Campard, Pascal
Published 2016

Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease

by Couturier, Julien, Stancu, Ilie-Cosmin, Schakman, Olivier, Pierrot, Nathalie, Huaux, François, Kienlen-Campard, Pascal, Dewachter, Ilse, Octave, Jean-Noël
Published 2016

Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing

by Decock, Marie, El Haylani, Laetitia, Stanga, Serena, Dewachter, Ilse, Octave, Jean-Noël, Smith, Steven O., Constantinescu, Stefan N., Kienlen-Campard, Pascal
Published 2015

Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice

by Stancu, Ilie-Cosmin, Vasconcelos, Bruno, Ris, Laurence, Wang, Peng, Villers, Agnès, Peeraer, Eve, Buist, Arjan, Terwel, Dick, Baatsen, Peter, Oyelami, Tutu, Pierrot, Nathalie, Casteels, Cindy, Bormans, Guy, Kienlen-Campard, Pascal, Octave, Jean-Nöel, Moechars, Diederik, Dewachter, Ilse
Published 2015

Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo

by Vasconcelos, Bruno, Stancu, Ilie-Cosmin, Buist, Arjan, Bird, Matthew, Wang, Peng, Vanoosthuyse, Alexandre, Van Kolen, Kristof, Verheyen, An, Kienlen-Campard, Pascal, Octave, Jean-Noël, Baatsen, Peter, Moechars, Diederik, Dewachter, Ilse
Published 2016

Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer’s disease early phenotypes

by Marquer, Catherine, Laine, Jeanne, Dauphinot, Luce, Hanbouch, Linda, Lemercier-Neuillet, Camille, Pierrot, Nathalie, Bossers, Koen, Le, Mickael, Corlier, Fabian, Benstaali, Caroline, Saudou, Frédéric, Thinakaran, Gopal, Cartier, Nathalie, Octave, Jean-Noël, Duyckaerts, Charles, Potier, Marie-Claude
Published 2014

Amyloid precursor protein controls cholesterol turnover needed for neuronal activity

by Pierrot, Nathalie, Tyteca, Donatienne, D'auria, Ludovic, Dewachter, Ilse, Gailly, Philippe, Hendrickx, Aurélie, Tasiaux, Bernadette, Haylani, Laetitia El, Muls, Nathalie, N'Kuli, Francisca, Laquerrière, Annie, Demoulin, Jean-Baptiste, Campion, Dominique, Brion, Jean-Pierre, Courtoy, Pierre J, Kienlen-Campard, Pascal, Octave, Jean-Noël
Published 2013