Evidence for a Crucial Role of Paneth Cells in Mediating the Intestinal Response to Injury

by Parry, Lee, Young, Madeleine, El Marjou, Fatima, Clarke, Alan R
Published 2013

Caspase-dependent proteolytic cleavage of STAT3α in ES cells, in mammary glands undergoing forced involution and in breast cancer cell lines

by Matthews, James R, Watson, Susan MR, Tevendale, Maxine CL, Watson, Christine J, Clarke, Alan R
Published 2007

Effects of Wnt3A and mechanical load on cartilage chondrocyte homeostasis

by Thomas, Rhian S, Clarke, Alan R, Duance, Victor C, Blain, Emma J
Published 2011

Absence of p53 in Clara cells favours multinucleation and loss of cell cycle arrest

by Armit, Christopher J, O'Dea, Shirley, Clarke, Alan R, Harrison, David J
Published 2002

Apc and p53 interaction in DNA damage and genomic instability in hepatocytes

by Méniel, Valérie, Megges, Matthias, Young, Madeleine A, Cole, Alicia, Sansom, Owen J, Clarke, Alan R
Published 2014

PPARδ status and mismatch repair mediated neoplasia in the mouse intestine

by Reed, Karen R, Sansom, Owen J, Hayes, Anthony J, Gescher, Andreas J, Peters, Jeffrey M, Clarke, Alan R
Published 2006

Brg1 Loss Attenuates Aberrant Wnt-Signalling and Prevents Wnt-Dependent Tumourigenesis in the Murine Small Intestine

by Holik, Aliaksei Z., Young, Madeleine, Krzystyniak, Joanna, Williams, Geraint T., Metzger, Daniel, Shorning, Boris Y., Clarke, Alan R.
Published 2014

In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system

by Jardé, Thierry, Evans, Rebecca J, McQuillan, Karina L, Parry, Lee, Feng, Gui Jie, Alvares, Bernardo, Clarke, Alan R, Dale, Trevor C
Published 2012

p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium

by Cole, Alicia M, Ridgway, Rachel A, Derkits, Sahra E, Parry, Lee, Barker, Nick, Clevers, Hans, Clarke, Alan R, Sansom, Owen J
Published 2010

Cited1 Deficiency Suppresses Intestinal Tumorigenesis

by Méniel, Valérie, Song, Fei, Phesse, Toby, Young, Madeleine, Poetz, Oliver, Parry, Lee, Jenkins, John R., Williams, Geraint T., Dunwoodie, Sally L., Watson, Alastair, Clarke, Alan R.
Published 2013

OncomiRdbB: a comprehensive database of microRNAs and their targets in breast cancer

by Khurana, Rimpi, Verma, Vinod Kumar, Rawoof, Abdul, Tiwari, Shrish, Nair, Rekha A, Mahidhara, Ganesh, Idris, Mohammed M, Clarke, Alan R, Kumar, Lekha Dinesh
Published 2014

Hunk/Mak-v is a negative regulator of intestinal cell proliferation

by Reed, Karen R, Korobko, Igor V, Ninkina, Natalia, Korobko, Elena V, Hopkins, Ben R, Platt, James L, Buchman, Vladimir, Clarke, Alan R
Published 2015

Ablation of β1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation

by Naylor, Matthew J., Li, Na, Cheung, Julia, Lowe, Emma T., Lambert, Elise, Marlow, Rebecca, Wang, Pengbo, Schatzmann, Franziska, Wintermantel, Timothy, Schüetz, Günther, Clarke, Alan R., Mueller, Ulrich, Hynes, Nancy E., Streuli, Charles H.
Published 2005

Epigenetic silencing of serine protease HTRA1 drives polyploidy

by Schmidt, Nina, Irle, Inga, Ripkens, Kamilla, Lux, Vanda, Nelles, Jasmin, Johannes, Christian, Parry, Lee, Greenow, Kirsty, Amir, Sarah, Campioni, Mara, Baldi, Alfonso, Oka, Chio, Kawaichi, Masashi, Clarke, Alan R., Ehrmann, Michael
Published 2016

E-cadherin can limit the transforming properties of activating β-catenin mutations

by Huels, David J, Ridgway, Rachel A, Radulescu, Sorina, Leushacke, Marc, Campbell, Andrew D, Biswas, Sujata, Leedham, Simon, Serra, Stefano, Chetty, Runjan, Moreaux, Guenievre, Parry, Lee, Matthews, James, Song, Fei, Hedley, Ann, Kalna, Gabriela, Ceteci, Fatih, Reed, Karen R, Meniel, Valerie S, Maguire, Aoife, Doyle, Brendan, Söderberg, Ola, Barker, Nick, Watson, Alastair, Larue, Lionel, Clarke, Alan R, Sansom, Owen J
Published 2015

Hepatic progenitor cells of biliary origin with liver repopulation capacity

by Lu, Wei-Yu, Bird, Thomas G, Boulter, Luke, Tsuchiya, Atsunori, Cole, Alicia M, Hay, Trevor, Guest, Rachel V, Wojtacha, Davina, Man, Tak Yung, Mackinnon, Alison, Ridgway, Rachel A, Kendall, Timothy, Williams, Michael J, Jamieson, Thomas, Raven, Alex, Hay, David C, Iredale, John P, Clarke, Alan R, Sansom, Owen J, Forbes, Stuart J
Published 2015