E-cadherin can limit the transforming properties of activating β-catenin mutations

E-cadherin can limit the transforming properties of activating β-catenin mutations

Wnt pathway deregulation is a common characteristic of many cancers. Only colorectal cancer predominantly harbours mutations in APC, whereas other cancer types (hepatocellular carcinoma, solid pseudopapillary tumours of the pancreas) have activating mutations in β-catenin (CTNNB1). We have compared...

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Bibliographic Details
Main Authors: Huels, David J, Ridgway, Rachel A, Radulescu, Sorina, Leushacke, Marc, Campbell, Andrew D, Biswas, Sujata, Leedham, Simon, Serra, Stefano, Chetty, Runjan, Moreaux, Guenievre, Parry, Lee, Matthews, James, Song, Fei, Hedley, Ann, Kalna, Gabriela, Ceteci, Fatih, Reed, Karen R, Meniel, Valerie S, Maguire, Aoife, Doyle, Brendan, Söderberg, Ola, Barker, Nick, Watson, Alastair, Larue, Lionel, Clarke, Alan R, Sansom, Owen J
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570519/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570519/

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