Evidence for a Crucial Role of Paneth Cells in Mediating the Intestinal Response to Injury
The identification of the intestinal stem cell (ISC) markers Lgr5 and Bmi-1 has furthered our understanding of how they accomplish homeostasis in this rapidly self-renewing tissue. Recent work indicates that these markers identify a cycling Lgr5+ ISC which can be replaced by a quiescent Bmi-1+ ISC....
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Wiley Subscription Services, Inc., A Wiley Company
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744757/ |