Replication efficiency of oncolytic vaccinia virus in cell cultures prognosticates the virulence and antitumor efficacy in mice

by Chen, Nanhai G, Yu, Yong A, Zhang, Qian, Szalay, Aladar A
Published 2011

Oncolytic Viruses

by Chen, Nanhai G., Szalay, Aladar A., Buller, R. Mark L., Lauer, Ulrich M.
Published 2012

Oncolytic vaccinia virus GLV-1h68 strain shows enhanced replication in human breast cancer stem-like cells in comparison to breast cancer cells

by Wang, Huiqiang, Chen, Nanhai G, Minev, Boris R, Szalay, Aladar A
Published 2012

Targeting hematologic malignancies with oncolytic vaccinia virus constructs

by Chen, Nanhai, Kilinc, Mehmet, Zhang, Qian, Aguilar, Jason, Tsoneva, Desislava, Pessian, Maysam, Minev, Boris, Szalay, Aladar
Published 2013

Expression of anti-VEGF antibody together with anti-EGFR or anti-FAP enhances tumor regression as a result of vaccinia virotherapy

by Huang, Ting, Wang, Huiqiang, Chen, Nanhai G, Frentzen, Alexa, Minev, Boris, Szalay, Aladar A
Published 2015

Microglia and astrocytes attenuate the replication of the oncolytic vaccinia virus LIVP 1.1.1 in murine GL261 gliomas by acting as vaccinia virus traps

by Kober, Christina, Rohn, Susanne, Weibel, Stephanie, Geissinger, Ulrike, Chen, Nanhai G, Szalay, Aladar A
Published 2015

Vaccinia virus expressing bone morphogenetic protein-4 in novel glioblastoma orthotopic models facilitates enhanced tumor regression and long-term survival

by Duggal, Rohit, Geissinger, Ulrike, Zhang, Qian, Aguilar, Jason, Chen, Nanhai G, Binda, Elena, Vescovi, Angelo L, Szalay, Aladar A
Published 2013

Growth inhibition of different human colorectal cancer xenografts after a single intravenous injection of oncolytic vaccinia virus GLV-1h68

by Ehrig, Klaas, Kilinc, Mehmet O, Chen, Nanhai G, Stritzker, Jochen, Buckel, Lisa, Zhang, Qian, Szalay, Aladar A
Published 2013

Vaccinia virus-mediated intra-tumoral expression of matrix metalloproteinase 9 enhances oncolysis of PC-3 xenograft tumors

by Schäfer, Simon, Weibel, Stephanie, Donat, Ulrike, Zhang, Qian, Aguilar, Richard J, Chen, Nanhai G, Szalay, Aladar A
Published 2012

Genomic sequence and analysis of a vaccinia virus isolate from a patient with a smallpox vaccine-related complication

by Li, Guiyun, Chen, Nanhai, Feng, Zehua, Buller, R Mark L, Osborne, John, Harms, Tiara, Damon, Inger, Upton, Chris, Esteban, David J
Published 2006

Functional hyper-IL-6 from vaccinia virus-colonized tumors triggers platelet formation and helps to alleviate toxicity of mitomycin C enhanced virus therapy

by Sturm, Julia B, Hess, Michael, Weibel, Stephanie, Chen, Nanhai G, Yu, Yong A, Zhang, Qian, Donat, Ulrike, Reiss, Cora, Gambaryan, Stepan, Krohne, Georg, Stritzker, Jochen, Szalay, Aladar A
Published 2012

Preferential Colonization of Metastases by Oncolytic Vaccinia Virus Strain GLV-1h68 in a Human PC-3 Prostate Cancer Model in Nude Mice

by Donat, Ulrike, Weibel, Stephanie, Hess, Michael, Stritzker, Jochen, Härtl, Barbara, Sturm, Julia B., Chen, Nanhai G., Gentschev, Ivaylo, Szalay, Aladar A.
Published 2012

Characterization of Metastasis Formation and Virotherapy in the Human C33A Cervical Cancer Model

by Donat, Ulrike, Rother, Juliane, Schäfer, Simon, Hess, Michael, Härtl, Barbara, Kober, Christina, Langbein-Laugwitz, Johanna, Stritzker, Jochen, Chen, Nanhai G., Aguilar, Richard J., Weibel, Stephanie, Szalay, Aladar A.
Published 2014

Molecular network, pathway, and functional analysis of time-dependent gene changes associated with pancreatic cancer susceptibility to oncolytic vaccinia virotherapy

by Haddad, Dana, Socci, Nicholas, Chen, Chun-Hao, Chen, Nanhai G, Zhang, Qian, Carpenter, Susanne G, Mittra, Arjun, Szalay, Aladar A, Fong, Yuman
Published 2016

Efficient Colonization and Therapy of Human Hepatocellular Carcinoma (HCC) Using the Oncolytic Vaccinia Virus Strain GLV-1h68

by Gentschev, Ivaylo, Müller, Meike, Adelfinger, Marion, Weibel, Stephanie, Grummt, Friedrich, Zimmermann, Martina, Bitzer, Michael, Heisig, Martin, Zhang, Qian, Yu, Yong A., Chen, Nanhai G., Stritzker, Jochen, Lauer, Ulrich M., Szalay, Aladar A.
Published 2011

Preclinical Evaluation of Oncolytic Vaccinia Virus for Therapy of Canine Soft Tissue Sarcoma

by Gentschev, Ivaylo, Adelfinger, Marion, Josupeit, Rafael, Rudolph, Stephan, Ehrig, Klaas, Donat, Ulrike, Weibel, Stephanie, Chen, Nanhai G., Yu, Yong A., Zhang, Qian, Heisig, Martin, Thamm, Douglas, Stritzker, Jochen, MacNeill, Amy, Szalay, Aladar A.
Published 2012

Insertion of the human sodium iodide symporter to facilitate deep tissue imaging does not alter oncolytic or replication capability of a novel vaccinia virus

by Haddad, Dana, Chen, Nanhai G, Zhang, Qian, Chen, Chun-Hao, Yu, Yong A, Gonzalez, Lorena, Carpenter, Susanne G, Carson, Joshua, Au, Joyce, Mittra, Arjun, Gonen, Mithat, Zanzonico, Pat B, Fong, Yuman, Szalay, Aladar A
Published 2011

Imaging Characteristics, Tissue Distribution, and Spread of a Novel Oncolytic Vaccinia Virus Carrying the Human Sodium Iodide Symporter

by Haddad, Dana, Chen, Chun-Hao, Carlin, Sean, Silberhumer, Gerd, Chen, Nanhai G., Zhang, Qian, Longo, Valerie, Carpenter, Susanne G., Mittra, Arjun, Carson, Joshua, Au, Joyce, Gonen, Mithat, Zanzonico, Pat B., Szalay, Aladar A., Fong, Yuman
Published 2012

Vaccinia virus GLV-1h153 is a novel agent for detection and effective local control of positive surgical margins for breast cancer

by Gholami, Sepideh, Chen, Chun-Hao, Belin, Laurence J, Lou, Emil, Fujisawa, Sho, Antonacci, Caroline, Carew, Amanda, Chen, Nanhai G, De Brot, Marina, Zanzonico, Pat B, Szalay, Aladar A, Fong, Yuman
Published 2013

A novel oncolytic viral therapy and imaging technique for gastric cancer using a genetically engineered vaccinia virus carrying the human sodium iodide symporter

by Jun, Kyong-Hwa, Gholami, Sepideh, Song, Tae-Jin, Au, Joyce, Haddad, Dana, Carson, Joshua, Chen, Chun-Hao, Mojica, Kelly, Zanzonico, Pat, Chen, Nanhai G, Zhang, Qian, Szalay, Aladar, Fong, Yuman
Published 2014