Molecular network, pathway, and functional analysis of time-dependent gene changes associated with pancreatic cancer susceptibility to oncolytic vaccinia virotherapy

Background: Pancreatic cancer is a fatal disease associated with resistance to conventional therapies. This study aimed to determine changes in gene expression patterns associated with infection and susceptibility of pancreatic cancer cells to an oncolyticvaccinia virus, GLV-1h153, carrying the huma...

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Bibliographic Details
Main Authors: Haddad, Dana, Socci, Nicholas, Chen, Chun-Hao, Chen, Nanhai G, Zhang, Qian, Carpenter, Susanne G, Mittra, Arjun, Szalay, Aladar A, Fong, Yuman
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824563/