Preferential Colonization of Metastases by Oncolytic Vaccinia Virus Strain GLV-1h68 in a Human PC-3 Prostate Cancer Model in Nude Mice

Recently, we showed that the oncolytic vaccinia virus GLV-1h68 has a significant therapeutic potential in treating lymph node metastases of human PC-3 prostate carcinoma in tumor xenografts. In this study, underlying mechanisms of the virus-mediated metastases reduction were analyzed. Immunohistoche...

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Bibliographic Details
Main Authors: Donat, Ulrike, Weibel, Stephanie, Hess, Michael, Stritzker, Jochen, Härtl, Barbara, Sturm, Julia B., Chen, Nanhai G., Gentschev, Ivaylo, Szalay, Aladar A.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457966/