Genome-Wide Association Analysis of Soluble ICAM-1 Concentration Reveals Novel Associations at the NFKBIK, PNPLA3, RELA, and SH2B3 Loci

by Paré, Guillaume, Ridker, Paul M., Rose, Lynda, Barbalic, Maja, Dupuis, Josée, Dehghan, Abbas, Bis, Joshua C., Benjamin, Emelia J., Shiffman, Dov, Parker, Alexander N., Chasman, Daniel I.
Published 2011

Whole Genome Sequence-Based Analysis of a Model Complex Trait, High Density Lipoprotein Cholesterol

by Morrison, Alanna C., Voorman, Arend, Johnson, Andrew D., Liu, Xiaoming, Yu, Jin, Li, Alexander, Muzny, Donna, Yu, Fuli, Rice, Kenneth, Zhu, Chengsong, Bis, Joshua, Heiss, Gerardo, O’Donnell, Christopher J., Psaty, Bruce M., Cupples, L. Adrienne, Gibbs, Richard, Boerwinkle, Eric
Published 2013

Sequence Analysis of Six Blood Pressure Candidate Regions in 4,178 Individuals: The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study

by Morrison, Alanna C., Bis, Joshua C., Hwang, Shih-Jen, Ehret, Georg B., Lumley, Thomas, Rice, Kenneth, Muzny, Donna, Gibbs, Richard A., Boerwinkle, Eric, Psaty, Bruce M., Chakravarti, Aravinda, Levy, Daniel
Published 2014

A novel Alzheimer disease locus located near the gene encoding tau protein

by Jun, Gyungah, Ibrahim-Verbaas, Carla A., Vronskaya, Maria, Lambert, Jean-Charles, Chung, Jaeyoon, Naj, Adam C., Kunkle, Brian W., Wang, Li-San, Bis, Joshua C., Bellenguez, Céline, Harold, Denise, Lunetta, Kathryn L., Destefano, Anita L., Grenier-Boley, Benjamin, Sims, Rebecca, Morgan, Kevin
Published 2015

Common folate gene variant, MTHFR C677T, is associated with brain structure in two independent cohorts of people with mild cognitive impairment☆

by Rajagopalan, Priya, Jahanshad, Neda, Stein, Jason L., Hua, Xue, Madsen, Sarah K., Kohannim, Omid, Hibar, Derrek P., Toga, Arthur W., Jack, Clifford R., Saykin, Andrew J., Green, Robert C., Weiner, Michael W., Bis, Joshua C., Kuller, Lewis H., Riverol, Mario, Becker, James T., Lopez, Oscar L., Thompson, Paul M.
Published 2012

Population Genomic Analysis of 962 Whole Genome Sequences of Humans Reveals Natural Selection in Non-Coding Regions

by Yu, Fuli, Lu, Jian, Liu, Xiaoming, Gazave, Elodie, Chang, Diana, Raj, Srilakshmi, Hunter-Zinck, Haley, Blekhman, Ran, Arbiza, Leonardo, Van Hout, Cris, Morrison, Alanna, Johnson, Andrew D., Bis, Joshua, Cupples, L. Adrienne, Psaty, Bruce M., Muzny, Donna, Yu, Jin, Gibbs, Richard A., Keinan, Alon, Clark, Andrew G., Boerwinkle, Eric
Published 2015

Genetic Evidence for a Normal-Weight “Metabolically Obese” Phenotype Linking Insulin Resistance, Hypertension, Coronary Artery Disease, and Type 2 Diabetes

by Yaghootkar, Hanieh, Scott, Robert A., White, Charles C., Zhang, Weihua, Speliotes, Elizabeth, Munroe, Patricia B., Ehret, Georg B., Bis, Joshua C., Fox, Caroline S., Walker, Mark, Borecki, Ingrid B., Knowles, Joshua W., Yerges-Armstrong, Laura, Ohlsson, Claes, Perry, John R.B., Chambers, John C., Kooner, Jaspal S., Franceschini, Nora, Langenberg, Claudia, Hivert, Marie-France, Dastani, Zari, Richards, J. Brent, Semple, Robert K., Frayling, Timothy M.
Published 2014

Genes From a Translational Analysis Support a Multifactorial Nature of White Matter Hyperintensities

by Lopez, Lorna M., Hill, W. David, Harris, Sarah E., Valdes Hernandez, Maria, Munoz Maniega, Susana, Bastin, Mark E., Bailey, Emma, Smith, Colin, McBride, Martin, McClure, John, Graham, Delyth, Dominiczak, Anna, Yang, Qiong, Fornage, Myriam, Ikram, M. Arfan, Debette, Stephanie, Launer, Lenore, Bis, Joshua C., Schmidt, Reinhold, Seshadri, Sudha, Porteous, David J., Starr, John, Deary, Ian J., Wardlaw, Joanna M.
Published 2015

Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium

by Grove, Megan L., Yu, Bing, Cochran, Barbara J., Haritunians, Talin, Bis, Joshua C., Taylor, Kent D., Hansen, Mark, Borecki, Ingrid B., Cupples, L. Adrienne, Fornage, Myriam, Gudnason, Vilmundur, Harris, Tamara B., Kathiresan, Sekar, Kraaij, Robert, Launer, Lenore J., Levy, Daniel, Liu, Yongmei, Mosley, Thomas, Peloso, Gina M., Psaty, Bruce M., Rich, Stephen S., Rivadeneira, Fernando, Siscovick, David S., Smith, Albert V., Uitterlinden, Andre, van Duijn, Cornelia M., Wilson, James G., O’Donnell, Christopher J., Rotter, Jerome I., Boerwinkle, Eric
Published 2013

Associations of NINJ2 Sequence Variants with Incident Ischemic Stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) Consortium

by Bis, Joshua C., DeStefano, Anita, Liu, Xiaoming, Brody, Jennifer A., Choi, Seung Hoan, Verhaaren, Benjamin F. J., Debette, Stéphanie, Ikram, M. Arfan, Shahar, Eyal, Butler, Kenneth R., Gottesman, Rebecca F., Muzny, Donna, Kovar, Christie L., Psaty, Bruce M., Hofman, Albert, Lumley, Thomas, Gupta, Mayetri, Wolf, Philip A., van Duijn, Cornelia, Gibbs, Richard A., Mosley, Thomas H., Longstreth, W. T., Boerwinkle, Eric, Seshadri, Sudha, Fornage, Myriam
Published 2014

Whole Exome Sequencing in Atrial Fibrillation

by Lubitz, Steven A., Brody, Jennifer A., Bihlmeyer, Nathan A., Roselli, Carolina, Weng, Lu-Chen, Christophersen, Ingrid E., Alonso, Alvaro, Boerwinkle, Eric, Gibbs, Richard A., Bis, Joshua C., Cupples, L. Adrienne, Mohler, Peter J., Nickerson, Deborah A., Muzny, Donna, Perez, Marco V., Psaty, Bruce M., Soliman, Elsayed Z., Sotoodehnia, Nona, Lunetta, Kathryn L., Benjamin, Emelia J., Heckbert, Susan R., Arking, Dan E., Ellinor, Patrick T., Lin, Honghuang
Published 2016

The Challenges of Genome-Wide Interaction Studies: Lessons to Learn from the Analysis of HDL Blood Levels

by van Leeuwen, Elisabeth M., Smouter, Françoise A. S., Kam-Thong, Tony, Karbalai, Nazanin, Smith, Albert V., Harris, Tamara B., Launer, Lenore J., Sitlani, Colleen M., Li, Guo, Brody, Jennifer A., Bis, Joshua C., White, Charles C., Jaiswal, Alok, Oostra, Ben A., Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, Andre G., Boerwinkle, Eric, Ballantyne, Christie M., Gudnason, Vilmundur, Psaty, Bruce M., Cupples, L. Adrienne, Järvelin, Marjo-Riitta, Ripatti, Samuli, Isaacs, Aaron, Müller-Myhsok, Bertram, Karssen, Lennart C., van Duijn, Cornelia M.
Published 2014

Prospective Associations of Coronary Heart Disease Loci in African Americans Using the MetaboChip: The PAGE Study

by Franceschini, Nora, Hu, Yijuan, Reiner, Alex P., Buyske, Steven, Nalls, Mike, Yanek, Lisa R., Li, Yun, Hindorff, Lucia A., Cole, Shelley A., Howard, Barbara V., Stafford, Jeanette M., Carty, Cara L., Sethupathy, Praveen, Martin, Lisa W., Lin, Dan-Yu, Johnson, Karen C., Becker, Lewis C., North, Kari E., Dehghan, Abbas, Bis, Joshua C., Liu, Yongmei, Greenland, Philip, Manson, JoAnn E., Maeda, Nobuyo, Garcia, Melissa, Harris, Tamara B., Becker, Diane M., O'Donnell, Christopher, Heiss, Gerardo, Kooperberg, Charles, Boerwinkle, Eric
Published 2014

Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-Wide Association Studies from the CHARGE Consortium

by Lemaitre, Rozenn N., Tanaka, Toshiko, Tang, Weihong, Manichaikul, Ani, Foy, Millennia, Kabagambe, Edmond K., Nettleton, Jennifer A., King, Irena B., Weng, Lu-Chen, Bhattacharya, Sayanti, Bandinelli, Stefania, Bis, Joshua C., Rich, Stephen S., Jacobs, David R., Cherubini, Antonio, McKnight, Barbara, Liang, Shuang, Gu, Xiangjun, Rice, Kenneth, Laurie, Cathy C., Lumley, Thomas, Browning, Brian L., Psaty, Bruce M., Chen, Yii-Der I., Friedlander, Yechiel, Djousse, Luc, Wu, Jason H. Y., Siscovick, David S., Uitterlinden, André G., Arnett, Donna K., Ferrucci, Luigi, Fornage, Myriam, Tsai, Michael Y., Mozaffarian, Dariush, Steffen, Lyn M.
Published 2011

Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans

by Mangino, Massimo, Hwang, Shih-Jen, Spector, Timothy D., Hunt, Steven C., Kimura, Masayuki, Fitzpatrick, Annette L., Christiansen, Lene, Petersen, Inge, Elbers, Clara C., Harris, Tamara, Chen, Wei, Srinivasan, Sathanur R., Kark, Jeremy D., Benetos, Athanase, El Shamieh, Said, Visvikis-Siest, Sophie, Christensen, Kaare, Berenson, Gerald S., Valdes, Ana M., Viñuela, Ana, Garcia, Melissa, Arnett, Donna K., Broeckel, Ulrich, Province, Michael A., Pankow, James S., Kammerer, Candace, Liu, Yongmei, Nalls, Michael, Tishkoff, Sarah, Thomas, Fridtjof, Ziv, Elad, Psaty, Bruce M., Bis, Joshua C., Rotter, Jerome I., Taylor, Kent D., Smith, Erin, Schork, Nicholas J., Levy, Daniel, Aviv, Abraham
Published 2012

Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram

by Verweij, Niek, Mateo Leach, Irene, Isaacs, Aaron, Arking, Dan E., Bis, Joshua C., Pers, Tune H., Van Den Berg, Marten E., Lyytikäinen, Leo-Pekka, Barnett, Phil, Wang, Xinchen, Soliman, Elsayed Z., Van Duijn, Cornelia M., Kähönen, Mika, Van Veldhuisen, Dirk J., Kors, Jan A., Raitakari, Olli T., Silva, Claudia T., Lehtimäki, Terho, Hillege, Hans L., Hirschhorn, Joel N., Boyer, Laurie A., Van Gilst, Wiek H., Alonso, Alvaro, Sotoodehnia, Nona, Eijgelsheim, Mark, De Boer, Rudolf A., De Bakker, Paul I. W., Franke, Lude, Van Der Harst, Pim
Published 2016

Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12

by Kilarski, Laura L., Achterberg, Sefanja, Devan, William J., Traylor, Matthew, Malik, Rainer, Lindgren, Arne, Pare, Guillame, Sharma, Pankaj, Slowik, Agniesczka, Thijs, Vincent, Walters, Matthew, Worrall, Bradford B., Sale, Michele M., Algra, Ale, Kappelle, L. Jaap, Wijmenga, Cisca, Norrving, Bo, Sandling, Johanna K., Rönnblom, Lars, Goris, An, Franke, Andre, Sudlow, Cathie, Rothwell, Peter M., Levi, Christopher, Holliday, Elizabeth G., Fornage, Myriam, Psaty, Bruce, Gretarsdottir, Solveig, Thorsteinsdottir, Unnar, Seshadri, Sudha, Mitchell, Braxton D., Kittner, Steven, Clarke, Robert, Hopewell, Jemma C., Bis, Joshua C., Boncoraglio, Giorgio B., Meschia, James, Ikram, M. Arfan, Hansen, Bjorn M., Montaner, Joan, Thorleifsson, Gudmar, Stefanson, Kari, Rosand, Jonathan, de Bakker, Paul I.W., Farrall, Martin, Dichgans, Martin, Markus, Hugh S., Bevan, Steve
Published 2014

A Novel MMP12 Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach

by Traylor, Matthew, Mäkelä, Kari-Matti, Kilarski, Laura L., Holliday, Elizabeth G., Devan, William J., Nalls, Mike A., Wiggins, Kerri L., Zhao, Wei, Cheng, Yu-Ching, Achterberg, Sefanja, Malik, Rainer, Sudlow, Cathie, Bevan, Steve, Raitoharju, Emma, Oksala, Niku, Thijs, Vincent, Lemmens, Robin, Lindgren, Arne, Slowik, Agnieszka, Maguire, Jane M., Walters, Matthew, Algra, Ale, Sharma, Pankaj, Attia, John R., Boncoraglio, Giorgio B., Rothwell, Peter M., de Bakker, Paul I. W., Bis, Joshua C., Saleheen, Danish, Kittner, Steven J., Mitchell, Braxton D., Rosand, Jonathan, Meschia, James F., Levi, Christopher, Dichgans, Martin, Lehtimäki, Terho, Lewis, Cathryn M., Markus, Hugh S.
Published 2014

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease

by Nalls, Mike A, Pankratz, Nathan, Lill, Christina M., Do, Chuong B, Hernandez, Dena G., Saad, Mohamad, DeStefano, Anita L., Kara, Eleanna, Bras, Jose, Sharma, Manu, Schulte, Claudia, Keller, Margaux F., Arepalli, Sampath, Letson, Christopher, Edsall, Connor, Stefansson, Hreinn, Liu, Xinmin, Pliner, Hannah, Lee, Joseph H., Cheng, Rong, Ikram, M. Arfan, Ioannidis, John P.A., Hadjigeorgiou, Georgios M., Bis, Joshua C., Martinez, Maria, Perlmutter, Joel S., Goate, Alison, Marder, Karen, Fiske, Brian, Sutherland, Margaret, Xiromerisiou, Georgia, Myers, Richard H., Clark, Lorraine N, Stefansson, Kari, Hardy, John A., Heutink, Peter, Chen, Honglei, Wood, Nicholas W., Houlden, Henry, Payami, Haydeh, Brice, Alexis, Scott, William K, Gasser, Thomas, Bertram, Lars, Eriksson, Nicholas, Foroud, Tatiana, Singleton, Andrew B.
Published 2014

Genome-Wide Association Study Identifies Novel Loci Associated with Circulating Phospho- and Sphingolipid Concentrations

by Demirkan, Ayşe, van Duijn, Cornelia M., Ugocsai, Peter, Isaacs, Aaron, Pramstaller, Peter P., Liebisch, Gerhard, Wilson, James F., Johansson, Åsa, Rudan, Igor, Aulchenko, Yurii S., Kirichenko, Anatoly V., Janssens, A. Cecile J. W., Jansen, Ritsert C., Gnewuch, Carsten, Domingues, Francisco S., Pattaro, Cristian, Wild, Sarah H., Jonasson, Inger, Polasek, Ozren, Zorkoltseva, Irina V., Hofman, Albert, Karssen, Lennart C., Struchalin, Maksim, Floyd, James, Igl, Wilmar, Biloglav, Zrinka, Broer, Linda, Pfeufer, Arne, Pichler, Irene, Campbell, Susan, Zaboli, Ghazal, Kolcic, Ivana, Rivadeneira, Fernando, Huffman, Jennifer, Hastie, Nicholas D., Uitterlinden, Andre, Franke, Lude, Franklin, Christopher S., Vitart, Veronique, Nelson, Christopher P., Preuss, Michael, Bis, Joshua C., O'Donnell, Christopher J., Franceschini, Nora, Witteman, Jacqueline C. M., Axenovich, Tatiana, Oostra, Ben A., Meitinger, Thomas, Hicks, Andrew A., Hayward, Caroline, Wright, Alan F., Gyllensten, Ulf, Campbell, Harry, Schmitz, Gerd
Published 2012