Delivering on the promise of precision cancer medicine

by Berger, Michael F., Van Allen, Eliezer M.
Published 2016

Advancing clinical oncology through genome biology and technology

by Varghese, Anna M, Berger, Michael F
Published 2014

Inferring condition-specific transcription factor function from DNA binding and gene expression data

by McCord, Rachel Patton, Berger, Michael F, Philippakis, Anthony A, Bulyk, Martha L
Published 2007

Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity

by Busser, Brian W., Shokri, Leila, Jaeger, Savina A., Gisselbrecht, Stephen S., Singhania, Aditi, Berger, Michael F., Zhou, Bo, Bulyk, Martha L., Michelson, Alan M.
Published 2012

Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA

by Cui, Huanhuan, Schlesinger, Jenny, Schoenhals, Sophia, Tönjes, Martje, Dunkel, Ilona, Meierhofer, David, Cano, Elena, Schulz, Kerstin, Berger, Michael F., Haack, Timm, Abdelilah-Seyfried, Salim, Bulyk, Martha L., Sauer, Sascha, Sperling, Silke R.
Published 2016

ERBB activation modulates sensitivity to MEK1/2 inhibition in a subset of driver-negative melanoma

by Hutchinson, Katherine E., Johnson, Douglas B., Johnson, Adam S., Sanchez, Violeta, Kuba, Maria, Lu, Pengcheng, Chen, Xi, Kelley, Mark C., Wang, Qingguo, Zhao, Zhongming, Kris, Mark, Berger, Michael F., Sosman, Jeffrey A., Pao, William
Published 2015

Genetic Alterations of Triple Negative Breast Cancer By Targeted Next Generation Sequencing And Correlation With Tumor Morphology

by Weisman, Paul S, Ng, Charlotte K.Y., Brogi, Edi, Eisenberg, Rachel E, Won, Helen H., Piscuoglio, Salvatore, De Filippo, Maria R., Ioris, Rafael, Akram, Muzaffar, Norton, Larry, Weigelt, Britta, Berger, Michael F., Reis-Filho, Jorge S., Wen, Hannah Y.
Published 2016

Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets

by Chen, Ying-Bei, Xu, Jianing, Skanderup, Anders Jacobsen, Dong, Yiyu, Brannon, A. Rose, Wang, Lu, Won, Helen H., Wang, Patricia I., Nanjangud, Gouri J., Jungbluth, Achim A., Li, Wei, Ojeda, Virginia, Hakimi, A. Ari, Voss, Martin H., Schultz, Nikolaus, Motzer, Robert J., Russo, Paul, Cheng, Emily H., Giancotti, Filippo G., Lee, William, Berger, Michael F., Tickoo, Satish K., Reuter, Victor E., Hsieh, James J.
Published 2016

Evaluating Cancer of the Central Nervous System Through Next-Generation Sequencing of Cerebrospinal Fluid

by Pentsova, Elena I., Shah, Ronak H., Tang, Jiabin, Boire, Adrienne, You, Daoqi, Briggs, Samuel, Omuro, Antonio, Lin, Xuling, Fleisher, Martin, Grommes, Christian, Panageas, Katherine S., Meng, Fanli, Selcuklu, S. Duygu, Ogilvie, Shahiba, Distefano, Natalie, Shagabayeva, Larisa, Rosenblum, Marc, DeAngelis, Lisa M., Viale, Agnes, Mellinghoff, Ingo K., Berger, Michael F.
Published 2016

Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions

by Brannon, A Rose, Vakiani, Efsevia, Sylvester, Brooke E, Scott, Sasinya N, McDermott, Gregory, Shah, Ronak H, Kania, Krishan, Viale, Agnes, Oschwald, Dayna M, Vacic, Vladimir, Emde, Anne-Katrin, Cercek, Andrea, Yaeger, Rona, Kemeny, Nancy E, Saltz, Leonard B, Shia, Jinru, D’Angelica, Michael I, Weiser, Martin R, Solit, David B, Berger, Michael F
Published 2014

PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors

by Lee, William, Teckie, Sewit, Wiesner, Thomas, Ran, Leili, Prieto Granada, Carlos N., Lin, Mingyan, Zhu, Sinan, Cao, Zhen, Liang, Yupu, Sboner, Andrea, Tap, William D., Fletcher, Jonathan A., Huberman, Kety H., Qin, Li-Xuan, Viale, Agnes, Singer, Samuel, Zheng, Deyou, Berger, Michael F., Chen, Yu, Antonescu, Cristina R., Chi, Ping
Published 2014

Convergent loss of PTEN leads to clinical resistance to a PI3Kα inhibitor

by Juric, Dejan, Castel, Pau, Griffith, Malachi, Griffith, Obi L., Won, Helen H., Ellis, Haley, Ebbesen, Saya H., Ainscough, Benjamin J., Ramu, Avinash, Iyer, Gopa, Shah, Ronak H., Huynh, Tiffany, Mino-Kenudson, Mari, Sgroi, Dennis, Isakoff, Steven, Thabet, Ashraf, Elamine, Leila, Solit, David B., Lowe, Scott W., Quadt, Cornelia, Peters, Malte, Derti, Adnan, Schegel, Robert, Huang, Alan, Mardis, Elaine R., Berger, Michael F., Baselga, José, Scaltriti., Maurizio
Published 2014

Melanoma genome sequencing reveals frequent PREX2 mutations

by Berger, Michael F., Hodis, Eran, Heffernan, Timothy P., Deribe, Yonathan Lissanu, Lawrence, Michael S., Protopopov, Alexei, Ivanova, Elena, Watson, Ian R., Nickerson, Elizabeth, Ghosh, Papia, Zhang, Hailei, Zeid, Rhamy, Ren, Xiaojia, Cibulskis, Kristian, Sivachenko, Andrey Y., Wagle, Nikhil, Sucker, Antje, Sougnez, Carrie, Onofrio, Robert, Ambrogio, Lauren, Auclair, Daniel, Fennell, Timothy, Carter, Scott L., Drier, Yotam, Stojanov, Petar, Singer, Meredith A., Voet, Douglas, Jing, Rui, Saksena, Gordon, Barretina, Jordi, Ramos, Alex H., Pugh, Trevor J., Stransky, Nicolas, Parkin, Melissa, Winckler, Wendy, Mahan, Scott, Ardlie, Kristin, Baldwin, Jennifer, Wargo, Jennifer, Schadendorf, Dirk, Meyerson, Matthew, Gabriel, Stacey B., Golub, Todd R., Wagner, Stephan N., Lander, Eric S., Getz, Gad, Chin, Lynda, Garraway, Levi A.
Published 2012

The genomic complexity of primary human prostate cancer

by Berger, Michael F., Lawrence, Michael S., Demichelis, Francesca, Drier, Yotam, Cibulskis, Kristian, Sivachenko, Andrey Y., Sboner, Andrea, Esgueva, Raquel, Pflueger, Dorothee, Sougnez, Carrie, Onofrio, Robert, Carter, Scott L., Park, Kyung, Habegger, Lukas, Ambrogio, Lauren, Fennell, Timothy, Parkin, Melissa, Saksena, Gordon, Voet, Douglas, Ramos, Alex H., Pugh, Trevor J., Wilkinson, Jane, Fisher, Sheila, Winckler, Wendy, Mahan, Scott, Ardlie, Kristin, Baldwin, Jennifer, Simons, Jonathan W., Kitabayashi, Naoki, MacDonald, Theresa Y., Kantoff, Philip W., Chin, Lynda, Gabriel, Stacey B., Gerstein, Mark B., Golub, Todd R., Meyerson, Matthew, Tewari, Ashutosh, Lander, Eric S., Getz, Gad, Rubin, Mark A., Garraway, Levi A.
Published 2011

The Cancer Cell Line Encyclopedia enables predictive modeling of anticancer drug sensitivity

by Barretina, Jordi, Caponigro, Giordano, Stransky, Nicolas, Venkatesan, Kavitha, Margolin, Adam A., Kim, Sungjoon, Wilson, Christopher J., Lehár, Joseph, Kryukov, Gregory V., Sonkin, Dmitriy, Reddy, Anupama, Liu, Manway, Murray, Lauren, Berger, Michael F., Monahan, John E., Morais, Paula, Meltzer, Jodi, Korejwa, Adam, Jané-Valbuena, Judit, Mapa, Felipa A., Thibault, Joseph, Bric-Furlong, Eva, Raman, Pichai, Shipway, Aaron, Engels, Ingo H., Cheng, Jill, Yu, Guoying K., Yu, Jianjun, Aspesi, Peter, de Silva, Melanie, Jagtap, Kalpana, Jones, Michael D., Wang, Li, Hatton, Charles, Palescandolo, Emanuele, Gupta, Supriya, Mahan, Scott, Sougnez, Carrie, Onofrio, Robert C., Liefeld, Ted, MacConaill, Laura, Winckler, Wendy, Reich, Michael, Li, Nanxin, Mesirov, Jill P., Gabriel, Stacey B., Getz, Gad, Ardlie, Kristin, Chan, Vivien, Myer, Vic E., Weber, Barbara L., Porter, Jeff, Warmuth, Markus, Finan, Peter, Harris, Jennifer L., Meyerson, Matthew, Golub, Todd R., Morrissey, Michael P., Sellers, William R., Schlegel, Robert, Garraway, Levi A.
Published 2012