Systemic Amyloidosis: Lessons from β2-Microglobulin*

by Stoppini, Monica, Bellotti, Vittorio
Published 2015

Historical and Current Concepts of Fibrillogenesis and In vivo Amyloidogenesis: Implications of Amyloid Tissue Targeting

by Kisilevsky, Robert, Raimondi, Sara, Bellotti, Vittorio
Published 2016

Assessment of Cellular Responses after Short- and Long-Term Exposure to Silver Nanoparticles in Human Neuroblastoma (SH-SY5Y) and Astrocytoma (D384) Cells

by Coccini, Teresa, Manzo, Luigi, Bellotti, Vittorio, De Simone, Uliana
Published 2014

Multifaceted anti-amyloidogenic and pro-amyloidogenic effects of C-reactive protein and serum amyloid P component in vitro

by Ozawa, Daisaku, Nomura, Ryo, Mangione, P. Patrizia, Hasegawa, Kazuhiro, Okoshi, Tadakazu, Porcari, Riccardo, Bellotti, Vittorio, Naiki, Hironobu
Published 2016

C. elegans Expressing Human β2-Microglobulin: A Novel Model for Studying the Relationship between the Molecular Assembly and the Toxic Phenotype

by Diomede, Luisa, Soria, Cristina, Romeo, Margherita, Giorgetti, Sofia, Marchese, Loredana, Mangione, Patrizia Palma, Porcari, Riccardo, Zorzoli, Irene, Salmona, Mario, Bellotti, Vittorio, Stoppini, Monica
Published 2012

Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability

by Camilloni, Carlo, Sala, Benedetta Maria, Sormanni, Pietro, Porcari, Riccardo, Corazza, Alessandra, De Rosa, Matteo, Zanini, Stefano, Barbiroli, Alberto, Esposito, Gennaro, Bolognesi, Martino, Bellotti, Vittorio, Vendruscolo, Michele, Ricagno, Stefano
Published 2016

Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2‐microglobulin

by Leri, Manuela, Bemporad, Francesco, Oropesa‐Nuñez, Reinier, Canale, Claudio, Calamai, Martino, Nosi, Daniele, Ramazzotti, Matteo, Giorgetti, Sofia, Pavone, Francesco S., Bellotti, Vittorio, Stefani, Massimo, Bucciantini, Monica
Published 2016

The two tryptophans of β2-microglobulin have distinct roles in function and folding and might represent two independent responses to evolutionary pressure

by Raimondi, Sara, Barbarini, Nicola, Mangione, Palma, Esposito, Gennaro, Ricagno, Stefano, Bolognesi, Martino, Zorzoli, Irene, Marchese, Loredana, Soria, Cristina, Bellazzi, Riccardo, Monti, Maria, Stoppini, Monica, Stefanelli, Mario, Magni, Paolo, Bellotti, Vittorio
Published 2011

Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic β2-Microglobulin*

by Halabelian, Levon, Ricagno, Stefano, Giorgetti, Sofia, Santambrogio, Carlo, Barbiroli, Alberto, Pellegrino, Sara, Achour, Adnane, Grandori, Rita, Marchese, Loredana, Raimondi, Sara, Mangione, P. Patrizia, Esposito, Gennaro, Al-Shawi, Raya, Simons, J. Paul, Speck, Ivana, Stoppini, Monica, Bolognesi, Martino, Bellotti, Vittorio
Published 2014

Co-fibrillogenesis of Wild-type and D76N β2-Microglobulin: THE CRUCIAL ROLE OF FIBRILLAR SEEDS*

by Natalello, Antonino, Mangione, P. Patrizia, Giorgetti, Sofia, Porcari, Riccardo, Marchese, Loredana, Zorzoli, Irene, Relini, Annalisa, Ami, Diletta, Faravelli, Giulia, Valli, Maurizia, Stoppini, Monica, Doglia, Silvia M., Bellotti, Vittorio, Raimondi, Sara
Published 2016

Structure, Folding Dynamics, and Amyloidogenesis of D76N β2-Microglobulin: ROLES OF SHEAR FLOW, HYDROPHOBIC SURFACES, AND α-CRYSTALLIN*

by Mangione, P. Patrizia, Esposito, Gennaro, Relini, Annalisa, Raimondi, Sara, Porcari, Riccardo, Giorgetti, Sofia, Corazza, Alessandra, Fogolari, Federico, Penco, Amanda, Goto, Yuji, Lee, Young-Ho, Yagi, Hisashi, Cecconi, Ciro, Naqvi, Mohsin M., Gillmore, Julian D., Hawkins, Philip N., Chiti, Fabrizio, Rolandi, Ranieri, Taylor, Graham W., Pepys, Mark B., Stoppini, Monica, Bellotti, Vittorio
Published 2013

Amyloid persistence in decellularized liver: biochemical and histopathological characterization

by Mazza, Giuseppe, Simons, J. Paul, Al-Shawi, Raya, Ellmerich, Stephan, Urbani, Luca, Giorgetti, Sofia, Taylor, Graham W., Gilbertson, Janet A., Hall, Andrew R., Al-Akkad, Walid, Dhar, Dipok, Hawkins, Philip N., De Coppi, Paolo, Pinzani, Massimo, Bellotti, Vittorio, Mangione, P. Patrizia
Published 2016

Bifunctional crosslinking ligands for transthyretin

by Mangione, P. Patrizia, Deroo, Stéphanie, Ellmerich, Stephan, Bellotti, Vittorio, Kolstoe, Simon, Wood, Stephen P., Robinson, Carol V., Smith, Martin D., Tennent, Glenys A., Broadbridge, Robert J., Council, Claire E., Thurston, Joanne R., Steadman, Victoria A., Vong, Antonio K., Swain, Christopher J., Pepys, Mark B., Taylor, Graham W.
Published 2015

A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis

by Marcoux, Julien, Mangione, P Patrizia, Porcari, Riccardo, Degiacomi, Matteo T, Verona, Guglielmo, Taylor, Graham W, Giorgetti, Sofia, Raimondi, Sara, Sanglier-Cianférani, Sarah, Benesch, Justin LP, Cecconi, Ciro, Naqvi, Mohsin M, Gillmore, Julian D, Hawkins, Philip N, Stoppini, Monica, Robinson, Carol V, Pepys, Mark B, Bellotti, Vittorio
Published 2015

D25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile

by Valleix, Sophie, Verona, Guglielmo, Jourde-Chiche, Noémie, Nédelec, Brigitte, Mangione, P. Patrizia, Bridoux, Frank, Mangé, Alain, Dogan, Ahmet, Goujon, Jean-Michel, Lhomme, Marie, Dauteuille, Carolane, Chabert, Michèle, Porcari, Riccardo, Waudby, Christopher A., Relini, Annalisa, Talmud, Philippa J., Kovrov, Oleg, Olivecrona, Gunilla, Stoppini, Monica, Christodoulou, John, Hawkins, Philip N., Grateau, Gilles, Delpech, Marc, Kontush, Anatol, Gillmore, Julian D., Kalopissis, Athina D., Bellotti, Vittorio
Published 2016

The H50Q Mutation Induces a 10-fold Decrease in the Solubility of α-Synuclein*

by Porcari, Riccardo, Proukakis, Christos, Waudby, Christopher A., Bolognesi, Benedetta, Mangione, P. Patrizia, Paton, Jack F. S., Mullin, Stephen, Cabrita, Lisa D., Penco, Amanda, Relini, Annalisa, Verona, Guglielmo, Vendruscolo, Michele, Stoppini, Monica, Tartaglia, Gian Gaetano, Camilloni, Carlo, Christodoulou, John, Schapira, Anthony H. V., Bellotti, Vittorio
Published 2015

Rapid Proton-Detected NMR Assignment for Proteins with Fast Magic Angle Spinning

by Barbet-Massin, Emeline, Pell, Andrew J., Retel, Joren S., Andreas, Loren B., Jaudzems, Kristaps, Franks, W. Trent, Nieuwkoop, Andrew J., Hiller, Matthias, Higman, Victoria, Guerry, Paul, Bertarello, Andrea, Knight, Michael J., Felletti, Michele, Le Marchand, Tanguy, Kotelovica, Svetlana, Akopjana, Inara, Tars, Kaspars, Stoppini, Monica, Bellotti, Vittorio, Bolognesi, Martino, Ricagno, Stefano, Chou, James J., Griffin, Robert G., Oschkinat, Hartmut, Lesage, Anne, Emsley, Lyndon, Herrmann, Torsten, Pintacuda, Guido
Published 2014