Multifaceted anti-amyloidogenic and pro-amyloidogenic effects of C-reactive protein and serum amyloid P component in vitro

Multifaceted anti-amyloidogenic and pro-amyloidogenic effects of C-reactive protein and serum amyloid P component in vitro

C-reactive protein (CRP) and serum amyloid P component (SAP), two major classical pentraxins in humans, are soluble pattern recognition molecules that regulate the innate immune system, but their chaperone activities remain poorly understood. Here, we examined their effects on the amyloid fibril for...

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Bibliographic Details
Main Authors: Ozawa, Daisaku, Nomura, Ryo, Mangione, P. Patrizia, Hasegawa, Kazuhiro, Okoshi, Tadakazu, Porcari, Riccardo, Bellotti, Vittorio, Naiki, Hironobu
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933921/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933921/

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