Thinking differently about lupus

by Wuster, Arthur, Behrens, Timothy W
Published 2016

Cd5 Maintains Tolerance in Anergic B Cells

by Hippen, Keli L., Tze, Lina E., Behrens, Timothy W.
Published 2000

Two Novel Routes of Transporter Associated with Antigen Processing (TAP)-independent Major Histocompatibility Complex Class I Antigen Processing

by Snyder, Heidi Link, Bačík, Igor, Bennink, Jack R., Kearns, Grainne, Behrens, Timothy W., Bächi, Thomas, Orlowski, Marian, Yewdell, Jonathan W.
Published 1997

Visualization of the Genesis and Fate of Isotype-switched B Cells during a Primary Immune Response

by Pape, Kathryn A., Kouskoff, Valerie, Nemazee, David, Tang, H. Lucy, Cyster, Jason G., Tze, Lina E., Hippen, Keli L., Behrens, Timothy W., Jenkins, Marc K.
Published 2003

Transgene Expression of bcl-xL Permits Anti-immunoglobulin (Ig)–induced Proliferation in xid B Cells

by Solvason, Nanette, Wu, Wei Wei, Kabra, Nisha, Lund-Johansen, Fridjtof, Roncarolo, Maria Grazia, Behrens, Timothy W., Grillot, Didier A.M., Nunez, Gabriel, Lees, Emma, Howard, Maureen
Published 1998

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus

by Cunninghame Graham, Deborah S., Morris, David L., Bhangale, Tushar R., Criswell, Lindsey A., Syvänen, Ann-Christine, Rönnblom, Lars, Behrens, Timothy W., Graham, Robert R., Vyse, Timothy J.
Published 2011

Relaxed Negative Selection in Germinal Centers and Impaired Affinity Maturation in bcl-x L Transgenic Mice

by Takahashi, Yoshimasa, Cerasoli, Douglas M., Dal Porto, Joseph M., Shimoda, Michiko, Freund, Robert, Fang, Wei, Telander, David G., Malvey, Erika-Nell, Mueller, Daniel L., Behrens, Timothy W., Kelsoe, Garnett
Published 1999

Elevated Serum Levels of Interferon-Regulated Chemokines Are Biomarkers for Active Human Systemic Lupus Erythematosus

by Bauer, Jason W, Baechler, Emily C, Petri, Michelle, Batliwalla, Franak M, Crawford, Dianna, Ortmann, Ward A, Espe, Karl J, Li, Wentian, Patel, Dhavalkumar D, Gregersen, Peter K, Behrens, Timothy W
Published 2006

Functional Studies on the IBD Susceptibility Gene IL23R Implicate Reduced Receptor Function in the Protective Genetic Variant R381Q

by Pidasheva, Svetlana, Trifari, Sara, Phillips, Anne, Hackney, Jason A., Ma, Yan, Smith, Ashley, Sohn, Sue J., Spits, Hergen, Little, Randall D., Behrens, Timothy W., Honigberg, Lee, Ghilardi, Nico, Clark, Hilary F.
Published 2011

Association of the interferon signature metric with serological disease manifestations but not global activity scores in multiple cohorts of patients with SLE

by Kennedy, William P, Maciuca, Romeo, Wolslegel, Kristen, Tew, Wei, Abbas, Alexander R, Chaivorapol, Christina, Morimoto, Alyssa, McBride, Jacqueline M, Brunetta, Paul, Richardson, Bruce C, Davis, John C, Behrens, Timothy W, Townsend, Michael J
Published 2015

High-Density SNP Mapping of the HLA Region Identifies Multiple Independent Susceptibility Loci Associated with Selective IgA Deficiency

by Ferreira, Ricardo C., Pan-Hammarström, Qiang, Graham, Robert R., Fontán, Gumersindo, Lee, Annette T., Ortmann, Ward, Wang, Ning, Urcelay, Elena, Fernández-Arquero, Miguel, Núñez, Concepción, Jorgensen, Gudmundur, Ludviksson, Björn R., Koskinen, Sinikka, Haimila, Katri, Padyukov, Leonid, Gregersen, Peter K., Hammarström, Lennart, Behrens, Timothy W.
Published 2012

Basal Immunoglobulin Signaling Actively Maintains Developmental Stage in Immature B Cells

by Tze, Lina E, Schram, Brian R, Lam, Kong-Peng, Hogquist, Kristin A, Hippen, Keli L, Liu, Jiabin, Shinton, Susan A, Otipoby, Kevin L, Rodine, Peter R, Vegoe, Amanda L, Kraus, Manfred, Hardy, Richard R, Schlissel, Mark S, Rajewsky, Klaus, Behrens, Timothy W
Published 2005

A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE

by Sandling, Johanna K, Garnier, Sophie, Sigurdsson, Snaevar, Wang, Chuan, Nordmark, Gunnel, Gunnarsson, Iva, Svenungsson, Elisabet, Padyukov, Leonid, Sturfelt, Gunnar, Jönsen, Andreas, Bengtsson, Anders A, Truedsson, Lennart, Eriksson, Catharina, Rantapää-Dahlqvist, Solbritt, Mälarstig, Anders, Strawbridge, Rona J, Hamsten, Anders, Criswell, Lindsey A, Graham, Robert R, Behrens, Timothy W, Eloranta, Maija-Leena, Alm, Gunnar, Rönnblom, Lars, Syvänen, Ann-Christine
Published 2011

Genetic linkage and transmission disequilibrium of marker haplotypes at chromosome 1q41 in human systemic lupus erythematosus

by Graham, Robert R, Langefeld, Carl D, Gaffney, Patrick M, Ortmann, Ward A, Selby, Scott A, Baechler, Emily C, Shark, Katherine B, Ockenden, Theresa C, Rohlf, Kristine E, Moser, Kathleen L, Brown, William M, Gabriel, Sherine E, Messner, Ronald P, King, Richard A, Horak, Pavel, Elder, James T, Stuart, Philip E, Rich, Steven S, Behrens, Timothy W
Published 2001

Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations

by Wang, Chuan, Ahlford, Annika, Järvinen, Tiina M, Nordmark, Gunnel, Eloranta, Maija-Leena, Gunnarsson, Iva, Svenungsson, Elisabet, Padyukov, Leonid, Sturfelt, Gunnar, Jönsen, Andreas, Bengtsson, Anders A, Truedsson, Lennart, Eriksson, Catharina, Rantapää-Dahlqvist, Solbritt, Sjöwall, Christopher, Julkunen, Heikki, Criswell, Lindsey A, Graham, Robert R, Behrens, Timothy W, Kere, Juha, Rönnblom, Lars, Syvänen, Ann-Christine, Sandling, Johanna K
Published 2013

CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B cell signaling and activation

by Manjarrez-Orduño, Nataly, Marasco, Emiliano, Chung, Sharon A., Katz, Matthew S., Kiridly, Jenna F., Simpfendorfer, Kim R., Freudenberg, Jan, Ballard, David H., Nashi, Emil, Hopkins, Thomas J., Graham, Deborah S Cunninghame, Lee, Annette T., Coenen, Marieke J. H., Franke, Barbara, Swinkels, Dorine W., Graham, Robert R., Kimberly, Robert P., Gaffney, Patrick M., Vyse, Timothy J., Behrens, Timothy W., Criswell, Lindsey A., Diamond, Betty, Gregersen, Peter K.
Published 2012

Common variants at PVT1, ATG13–AMBRA1, AHI1 and CLEC16A are associated with selective IgA deficiency

by Bronson, Paola G., Chang, Diana, Bhangale, Tushar, Seldin, Michael F., Ortmann, Ward, Ferreira, Ricardo C., Urcelay, Elena, Pereira, Luis Fernández, Martin, Javier, Plebani, Alessandro, Lougaris, Vassilios, Friman, Vanda, Freiberger, Tomáš, Litzman, Jiri, Thon, Vojtech, Pan-Hammarström, Qiang, Hammarström, Lennart, Graham, Robert R., Behrens, Timothy W.
Published 2016

Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus

by Bentham, James, Morris, David L, Graham, Deborah S Cunninghame, Pinder, Christopher L, Tombleson, Philip, Behrens, Timothy W, Martín, Javier, Fairfax, Benjamin P, Knight, Julian C, Chen, Lingyan, Replogle, Joseph, Syvänen, Ann-Christine, Rönnblom, Lars, Graham, Robert R, Wither, Joan E, Rioux, John D, Alarcón-Riquelme, Marta E, Vyse, Timothy J
Published 2015

Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration

by Yu, Yi, Bhangale, Tushar R., Fagerness, Jesen, Ripke, Stephan, Thorleifsson, Gudmar, Tan, Perciliz L., Souied, Eric H., Richardson, Andrea J., Merriam, Joanna E., Buitendijk, Gabriëlle H.S., Reynolds, Robyn, Raychaudhuri, Soumya, Chin, Kimberly A., Sobrin, Lucia, Evangelou, Evangelos, Lee, Phil H., Lee, Aaron Y., Leveziel, Nicolas, Zack, Donald J., Campochiaro, Betsy, Campochiaro, Peter, Smith, R. Theodore, Barile, Gaetano R., Guymer, Robyn H., Hogg, Ruth, Chakravarthy, Usha, Robman, Luba D., Gustafsson, Omar, Sigurdsson, Haraldur, Ortmann, Ward, Behrens, Timothy W., Stefansson, Kari, Uitterlinden, André G., van Duijn, Cornelia M., Vingerling, Johannes R., Klaver, Caroline C.W., Allikmets, Rando, Brantley, Milam A., Baird, Paul N., Katsanis, Nicholas, Thorsteinsdottir, Unnur, Ioannidis, John P.A., Daly, Mark J., Graham, Robert R., Seddon, Johanna M.
Published 2011

Genetics of rheumatoid arthritis contributes to biology and drug discovery

by Okada, Yukinori, Wu, Di, Trynka, Gosia, Raj, Towfique, Terao, Chikashi, Ikari, Katsunori, Kochi, Yuta, Ohmura, Koichiro, Suzuki, Akari, Yoshida, Shinji, Graham, Robert R., Manoharan, Arun, Ortmann, Ward, Bhangale, Tushar, Denny, Joshua C., Carroll, Robert J., Eyler, Anne E., Greenberg, Jeffrey D., Kremer, Joel M., Pappas, Dimitrios A., Jiang, Lei, Yin, Jian, Ye, Lingying, Su, Ding-Feng, Yang, Jian, Xie, Gang, Keystone, Ed, Westra, Harm-Jan, Esko, Tõnu, Metspalu, Andres, Zhou, Xuezhong, Gupta, Namrata, Mirel, Daniel, Stahl, Eli A., Diogo, Dorothée, Cui, Jing, Liao, Katherine, Guo, Michael H., Myouzen, Keiko, Kawaguchi, Takahisa, Coenen, Marieke J.H., van Riel, Piet L.C.M., van de Laar, Mart A.F.J., Guchelaar, Henk-Jan, Huizinga, Tom W.J., Dieudé, Philippe, Mariette, Xavier, Bridges, S. Louis, Zhernakova, Alexandra, Toes, Rene E.M., Tak, Paul P., Miceli-Richard, Corinne, Bang, So-Young, Lee, Hye-Soon, Martin, Javier, Gonzalez-Gay, Miguel A., Rodriguez-Rodriguez, Luis, Rantapää-Dahlqvist, Solbritt, Ärlestig, Lisbeth, Choi, Hyon K., Kamatani, Yoichiro, Galan, Pilar, Lathrop, Mark, Eyre, Steve, Bowes, John, Barton, Anne, de Vries, Niek, Moreland, Larry W., Criswell, Lindsey A., Karlson, Elizabeth W., Taniguchi, Atsuo, Yamada, Ryo, Kubo, Michiaki, Liu, Jun S., Bae, Sang-Cheol, Worthington, Jane, Padyukov, Leonid, Klareskog, Lars, Gregersen, Peter K., Raychaudhuri, Soumya, Stranger, Barbara E., De Jager, Philip L., Franke, Lude, Visscher, Peter M., Brown, Matthew A., Yamanaka, Hisashi, Mimori, Tsuneyo, Takahashi, Atsushi, Xu, Huji, Behrens, Timothy W., Siminovitch, Katherine A., Momohara, Shigeki, Matsuda, Fumihiko, Yamamoto, Kazuhiko, Plenge, Robert M.
Published 2013