A gain-of-function mouse model identifies PRMT6 as a NF-κB coactivator

by Di Lorenzo, Alessandra, Yang, Yanzhong, Macaluso, Marc, Bedford, Mark T.
Published 2014

Using oriented peptide array libraries to evaluate methylarginine-specific antibodies and arginine methyltransferase substrate motifs

by Gayatri, Sitaram, Cowles, Martis W., Vemulapalli, Vidyasiri, Cheng, Donghang, Sun, Zu-Wen, Bedford, Mark T.
Published 2016

Interaction of Proliferation Cell Nuclear Antigen (PCNA) with c-Abl in Cell Proliferation and Response to DNA Damages in Breast Cancer

by Zhao, Huajun, Ho, Po-Chun, Lo, Yuan-Hung, Espejo, Alexsandra, Bedford, Mark T., Hung, Mien-Chie, Wang, Shao-Chun
Published 2012

Crystal Structure of TDRD3 and Methyl-Arginine Binding Characterization of TDRD3, SMN and SPF30

by Liu, Ke, Guo, Yahong, Liu, Haiping, Bian, Chuanbing, Lam, Robert, Liu, Yongsong, Mackenzie, Farrell, Rojas, Luis Alejandro, Reinberg, Danny, Bedford, Mark T., Xu, Rui-Ming, Min, Jinrong
Published 2012

Methylation by Set9 modulates FoxO3 stability and transcriptional activity

by Calnan, Daniel R., Webb, Ashley E., White, Jamie L., Stowe, Timothy R., Goswami, Tapasree, Shi, Xiaobing, Espejo, Alexsandra, Bedford, Mark T., Gozani, Or, Gygi, Steven P., Brunet, Anne
Published 2012

Loss of the major Type I arginine methyltransferase PRMT1 causes substrate scavenging by other PRMTs

by Dhar, Surbhi, Vemulapalli, Vidyasiri, Patananan, Alexander N., Huang, Grace L., Di Lorenzo, Alessandra, Richard, Stephane, Comb, Michael J., Guo, Ailan, Clarke, Steven G., Bedford, Mark T.
Published 2013

Methyllysine Reader Plant Homeodomain (PHD) Finger Protein 20-like 1 (PHF20L1) Antagonizes DNA (Cytosine-5) Methyltransferase 1 (DNMT1) Proteasomal Degradation*

by Estève, Pierre-Olivier, Terragni, Jolyon, Deepti, Kanneganti, Chin, Hang Gyeong, Dai, Nan, Espejo, Alexsandra, Corrêa, Ivan R., Bedford, Mark T., Pradhan, Sriharsa
Published 2014

G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression

by Zhang, Xi, Peng, Danni, Xi, Yuanxin, Yuan, Chao, Sagum, Cari A., Klein, Brianna J., Tanaka, Kaori, Wen, Hong, Kutateladze, Tatiana G., Li, Wei, Bedford, Mark T., Shi, Xiaobing
Published 2016

PRMT9 is a Type II methyltransferase that methylates the splicing factor SAP145

by Yang, Yanzhong, Hadjikyriacou, Andrea, Xia, Zheng, Gayatri, Sitaram, Kim, Daehoon, Zurita-Lopez, Cecilia, Kelly, Ryan, Guo, Ailan, Li, Wei, Clarke, Steven G., Bedford, Mark T.
Published 2015

Association of UHRF1 with H3K9 methylation directs the maintenance of DNA methylation

by Rothbart, Scott B., Krajewski, Krzysztof, Nady, Nataliya, Tempel, Wolfram, Xue, Sheng, Badeaux, Aimee I., Barsyte-Lovejoy, Dalia, Martinez, Jorge Y., Bedford, Mark T., Fuchs, Stephen M., Arrowsmith, Cheryl H., Strahl, Brian D.
Published 2012

Immunoaffinity Enrichment and Mass Spectrometry Analysis of Protein Methylation

by Guo, Ailan, Gu, Hongbo, Zhou, Jing, Mulhern, Daniel, Wang, Yi, Lee, Kimberly A., Yang, Vicky, Aguiar, Mike, Kornhauser, Jon, Jia, Xiaoying, Ren, Jianmin, Beausoleil, Sean A., Silva, Jeffrey C., Vemulapalli, Vidyasiri, Bedford, Mark T., Comb, Michael J.
Published 2014

Binding of 14-3-3 reader proteins to phosphorylated DNMT1 facilitates aberrant DNA methylation and gene expression

by Estève, Pierre-Olivier, Zhang, Guoqiang, Ponnaluri, V.K. Chaithanya, Deepti, Kanneganti, Chin, Hang Gyeong, Dai, Nan, Sagum, Cari, Black, Karynne, Corrêa, Ivan R., Bedford, Mark T., Cheng, Xiaodong, Pradhan, Sriharsa
Published 2016

SETD6 lysine methylation of RelA couples GLP activity at chromatin to tonic repression of NF-κB signaling

by Levy, Dan, Kuo, Alex J., Chang, Yanqi, Schaefer, Uwe, Kitson, Christopher, Cheung, Peggie, Espejo, Alexsandra, Zee, Barry M., Liu, Chih Long, Tangsombatvisit, Stephanie, Tennen, Ruth I., Kuo, Andrew Y., Tanjing, Song, Cheung, Regina, Chua, Katrin F., Utz, Paul J., Shi, Xiaobing, Prinjha, Rab K., Lee, Kevin, Garcia, Benjamin A., Bedford, Mark T., Tarakhovsky, Alexander, Cheng, Xiaodong, Gozani, Or
Published 2010

Discovery of a chemical probe for the L3MBTL3 methyl-lysine reader domain

by James, Lindsey I., Barsyte-Lovejoy, Dalia, Zhong, Nan, Krichevsky, Liubov, Korboukh, Victoria K., Herold, Martin J., MacNevin, Christopher J., Norris, Jacqueline L., Sagum, Cari A., Tempel, Wolfram, Marcon, Edyta, Guo, Hongbo, Gao, Cen, Huang, Xi-Ping, Duan, Shili, Emili, Andrew, Greenblatt, Jack F., Kireev, Dmitri B., Jin, Jian, Janzen, William P., Brown, Peter J., Bedford, Mark T., Arrowsmith, Cheryl H., Frye, Stephen V.
Published 2013

TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1

by Hossain, Mohammad B., Shifat, Rehnuma, Johnson, David G., Bedford, Mark T., Gabrusiewicz, Konrad R., Cortes-Santiago, Nahir, Luo, Xuemei, Lu, Zhimin, Ezhilarasan, Ravesanker, Sulman, Erik P., Jiang, Hong, Li, Shawn S. C., Lang, Frederick F., Tyler, Jessica, Hung, Mien-Chie, Fueyo, Juan, Gomez-Manzano, Candelaria
Published 2016

Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 gene

by Perez, Carlos J., Mecklenburg, Lars, Jaubert, Jean, Santamaria, Lucia Martinez, Iritani, Brian M., Espejo, Alexsandra, Napoli, Eleonora, Song, Gyu, del Río, Marcela, DiGiovanni, John, Giulivi, Cecilia, Bedford, Mark T., Dent, Sharon Y.R., Wood, Richard D., Kusewitt, Donna F., Guénet, Jean Louis, Conti, Claudio J., Benavides, Fernando
Published 2015

A cellular chemical probe targeting the chromodomains of Polycomb Repressive Complex 1

by Stuckey, Jacob I, Dickson, Bradley M, Cheng, Nancy, Liu, Yanli, Norris, Jacqueline L, Cholensky, Stephanie H, Tempel, Wolfram, Qin, Su, Huber, Katherine G, Sagum, Cari, Black, Karynne, Li, Fengling, Huang, Xi-Ping, Roth, Bryan L, Baughman, Brandi M, Senisterra, Guillermo, Pattenden, Samantha G, Vedadi, Masoud, Brown, Peter J, Bedford, Mark T, Min, Jinrong, Arrowsmith, Cheryl H, James, Lindsey I, Frye, Stephen V
Published 2016