SETD6 lysine methylation of RelA couples GLP activity at chromatin to tonic repression of NF-κB signaling

SETD6 lysine methylation of RelA couples GLP activity at chromatin to tonic repression of NF-κB signaling

Protein lysine methylation signaling is implicated in diverse biological and disease processes. Yet the catalytic activity and substrate specificity are unknown for many human protein lysine methyltransferases (PKMTs). We screened over forty candidate PKMTs and identified SETD6 as a methyltransferas...

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Bibliographic Details
Main Authors: Levy, Dan, Kuo, Alex J., Chang, Yanqi, Schaefer, Uwe, Kitson, Christopher, Cheung, Peggie, Espejo, Alexsandra, Zee, Barry M., Liu, Chih Long, Tangsombatvisit, Stephanie, Tennen, Ruth I., Kuo, Andrew Y., Tanjing, Song, Cheung, Regina, Chua, Katrin F., Utz, Paul J., Shi, Xiaobing, Prinjha, Rab K., Lee, Kevin, Garcia, Benjamin A., Bedford, Mark T., Tarakhovsky, Alexander, Cheng, Xiaodong, Gozani, Or
Format: Online
Language:English
Published: 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074206/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074206/

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