Enantioselective Nickel-Catalysed Arylative and Alkenylative Cyclisations onto Electron-Deficient Alkenes via E/Z Isomerisation

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Enantioselective Nickel-Catalysed Arylative and Alkenylative Cyclisations onto Electron-Deficient Alkenes via E/Z Isomerisation

Herein is presented a highly enantioselective nickel-catalysed anti-carbometallative-cyclisation reaction of substrates containing an alkyne tethered to an electron-deficient alkene. Enantioenriched cyclopentene products, that are otherwise difficult to synthesise, are obtained in up to 99% yield an...

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Bibliographic Details
Main Author:	Gillbard, Simone Marie
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2023
Subjects:	heterocycles electrophiles catalysis domino reactions
Online Access:	https://eprints.nottingham.ac.uk/73697/

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