Enantioselective Nickel-Catalysed Arylative and Alkenylative Cyclisations onto Electron-Deficient Alkenes via E/Z Isomerisation
Herein is presented a highly enantioselective nickel-catalysed anti-carbometallative-cyclisation reaction of substrates containing an alkyne tethered to an electron-deficient alkene. Enantioenriched cyclopentene products, that are otherwise difficult to synthesise, are obtained in up to 99% yield an...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2023
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| Online Access: | https://eprints.nottingham.ac.uk/73697/ |