Optimisation of Delivery of the Ataxia Telangiectasia Mutated Transgene to HeLa Cells Using Glycosaminoglycan Enhanced Transduction

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Optimisation of Delivery of the Ataxia Telangiectasia Mutated Transgene to HeLa Cells Using Glycosaminoglycan Enhanced Transduction

Ataxia telangiectasia (AT) is a monogenic syndrome that is characterised by hypersensitivity to ionising irradiation. This study is part of a proof-of-concept project for a non-viral gene therapy that utilises glycosaminoglycan-enhanced transduction (GET), which is based on transfection peptides tha...

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Bibliographic Details
Main Author:	Siam, Ala'a
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2021
Subjects:	Ataxia telangiectasia non-viral gene therapy
Online Access:	https://eprints.nottingham.ac.uk/66891/

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