Optimisation of Delivery of the Ataxia Telangiectasia Mutated Transgene to HeLa Cells Using Glycosaminoglycan Enhanced Transduction
Ataxia telangiectasia (AT) is a monogenic syndrome that is characterised by hypersensitivity to ionising irradiation. This study is part of a proof-of-concept project for a non-viral gene therapy that utilises glycosaminoglycan-enhanced transduction (GET), which is based on transfection peptides tha...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2021
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| Online Access: | https://eprints.nottingham.ac.uk/66891/ |