Investigating novel cationic polymers for siRNA delivery for treatment of allergic disease
Spleen tyrosine kinase (Syk) is an enzyme which plays a prominent role in IgE-dependent signal transduction in type 1 hypersensitivity reactions. Due to the important role of Syk in the early signalling cascade in mast cells and basophils for inducing allergic reaction, it could be a suitable target...
| Main Author: | Almughem, Fahad |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2018
|
| Online Access: | https://eprints.nottingham.ac.uk/52376/ |
Similar Items
Study on Liposomes Integrity and Delivery of siRNA to Lung Cancer
by: Aljasser, Abdullah
Published: (2024)
by: Aljasser, Abdullah
Published: (2024)
Phosphonium polymethacrylates for siRNA delivery: effect of polymer and RNA structural parameters on polyplex assembly and gene knockdown
by: Loczenski Rose, Vanessa, et al.
Published: (2015)
by: Loczenski Rose, Vanessa, et al.
Published: (2015)
In-vitro investigations into endocytosis and silencing of siRNA-liposomes
by: ALSHEHRI, ABDULLAH ALI D
Published: (2017)
by: ALSHEHRI, ABDULLAH ALI D
Published: (2017)
Development and application of a linear polyamidoamine-SiRNA delivery system
by: Fathi, Zainab H
Published: (2018)
by: Fathi, Zainab H
Published: (2018)
Pathways of cellular internalisation of liposomes delivered siRNA and effects on siRNA engagement with target mRNA and silencing in cancer cells
by: Alshehri, Abdullah Ali, et al.
Published: (2018)
by: Alshehri, Abdullah Ali, et al.
Published: (2018)
Water-soluble substituted chitosan derivatives as technology platform for inhalation delivery of siRNA
by: Capel, Victoria, et al.
Published: (2018)
by: Capel, Victoria, et al.
Published: (2018)
MysiRNA-designer: a workflow for efficient siRNA design
by: Mysara, Mohamed, et al.
Published: (2011)
by: Mysara, Mohamed, et al.
Published: (2011)
Systemic in vivo delivery of siRNA to tumours using combination of polyethyleneimine and transferrin–polyethyleneimine conjugates
by: Grabowska, Anna M., et al.
Published: (2015)
by: Grabowska, Anna M., et al.
Published: (2015)
Oncogenic signaling in tumorigenesis and applications of siRNA nanotherapeutics in breast cancer
by: Nur Izyani K,, et al.
Published: (2019)
by: Nur Izyani K,, et al.
Published: (2019)
Triblock copolymer nanovesicles for pH-responsive targeted delivery and controlled release of siRNA to cancer cells
by: Gallon, Elena, et al.
Published: (2015)
by: Gallon, Elena, et al.
Published: (2015)
Engineering human epidermal growth receptor 2‑Targeting hepatitis B virus core nanoparticles for siRNA delivery in vitro and in vivo
by: Mohamed Suffian, Izzat Fahimuddin, et al.
Published: (2018)
by: Mohamed Suffian, Izzat Fahimuddin, et al.
Published: (2018)
Insight into the relationship between the cell culture model, cell trafficking and siRNA silencing efficiency
by: Capel, Victoria, et al.
Published: (2016)
by: Capel, Victoria, et al.
Published: (2016)
Rapid formulation of redox-responsive oligo-β-aminoester polyplexes with siRNA via jet printing
by: Lovato, Tatiana, et al.
Published: (2018)
by: Lovato, Tatiana, et al.
Published: (2018)
siRNA blocking of mammalian target of rapamycin (mTOR) attenuates pathology in annonacin-induced tauopathy in mice
by: Salama, Mohamed M., et al.
Published: (2019)
by: Salama, Mohamed M., et al.
Published: (2019)
Effects of knocking-down HIF-la (siRNA) on vgsc expression in the aggressive human breast cancer cells (MDA-MB-231)
by: Hussin, Mohd Zaki
Published: (2015)
by: Hussin, Mohd Zaki
Published: (2015)
Star-Shaped Amphiphilic Hyperbranched Polyglycerol Conjugated with Dendritic Poly(l-lysine) for the Codelivery of Docetaxel and MMP-9 siRNA in Cancer Therapy.
by: Zhou, X., et al.
Published: (2016)
by: Zhou, X., et al.
Published: (2016)
Effects of silencing dishevelled 1, 2 and 3 mRNA expression on MDA-MB-231 cell migration and invasion using siRNAs
by: Khoo, Samuel Leon Juan
Published: (2015)
by: Khoo, Samuel Leon Juan
Published: (2015)
An in silico approach to design potential siRNA molecules for ICP22 (US1) gene silencing of different strains of human herpes simplex 1
by: Nur, Suza, et al.
Published: (2013)
by: Nur, Suza, et al.
Published: (2013)
Downregulation Of Skp2 Via siRNA Mediated Gene Knockdown And Its Effects On FOXO3 AND c-MYC Expression In AML t(8,21) Cells
by: Purushodman, Kasturi
Published: (2017)
by: Purushodman, Kasturi
Published: (2017)
Helminths and allergic disease in Vietnam
by: Flohr, Carsten
Published: (2007)
by: Flohr, Carsten
Published: (2007)
Probiotic effects in allergic disease
by: Ismail, Intan Hakimah, et al.
Published: (2013)
by: Ismail, Intan Hakimah, et al.
Published: (2013)
Effects of CXCR4 siRNA/dextran-spermine nanoparticles on CXCR4 expression and serum LDH levels in a mouse model of colorectal cancer metastasis to the liver.
by: Abedini, Fatemeh, et al.
Published: (2011)
by: Abedini, Fatemeh, et al.
Published: (2011)
Suppression Of Aml1/ETO Via siRNA Mediated Gene Knockdown And Its Effects On FOXO3 AND c-Myc Expression In Aml t (8,21) Cells
by: Ong, Si Min
Published: (2017)
by: Ong, Si Min
Published: (2017)
Investigating Current Delivery Vehicles for Efficient and Targeted Delivery of Therapeutic RNA and Future Perspectives
Part A - Investigating current delivery vehicles for efficient and targeted delivery of therapeutic RNA and future perspectives/ Part B - The development of novel polymeric nanoparticles as efficient non-viral RNA delivery vectors
by: Sachan, Isha
Published: (2023)
by: Sachan, Isha
Published: (2023)
Computational Studies of Novel Chymase Inhibitors Against Cardiovascular and Allergic Diseases: Mechanism and Inhibition
by: Arooj, Mahreen, et al.
Published: (2012)
by: Arooj, Mahreen, et al.
Published: (2012)
Cationic polymers and their therapeutic potential
by: Fiore, A., et al.
Published: (2012)
by: Fiore, A., et al.
Published: (2012)
Cationic liposome- multi-walled carbon nanotubes hybrids for dual siPLK1 and doxorubicin delivery in vitro
by: Pereira, Sara, et al.
Published: (2015)
by: Pereira, Sara, et al.
Published: (2015)
Epha2 sirna silencing on malignant glioma cells
by: Azman , Amy Shafinas
Published: (2017)
by: Azman , Amy Shafinas
Published: (2017)
Interleukin-4 receptor alpha gene variants and allergic disease
by: Hall, Ian P.
Published: (2000)
by: Hall, Ian P.
Published: (2000)
Investigating the regulation of DNA and RNA modifications in neurocognitive diseases
by: Perez Grovas Saltijeral, Adriana
Published: (2025)
by: Perez Grovas Saltijeral, Adriana
Published: (2025)
Multiple gene targeting siRNAs for down regulation of Immediate Early-2 (Ie2) and DNA polymerase genes mediated inhibition of novel rat Cytomegalovirus (strain All-03)
by: Balakrishnan, Krishnan Nair, et al.
Published: (2020)
by: Balakrishnan, Krishnan Nair, et al.
Published: (2020)
The effect of channa striatus as an adjuvant therapy in treatment of allergic rhinitis
by: Dhevi Susibalan, Bathma
Published: (2015)
by: Dhevi Susibalan, Bathma
Published: (2015)
Investigating tight junction proteinrelated regulation of nasal epithelial barrier integrity in allergic rhinitis patients and non-allergic individuals
by: Othman, Siti Sarah Che
Published: (2023)
by: Othman, Siti Sarah Che
Published: (2023)
Cationic supramolecular hydrogels for overcoming the
skin barrier in drug delivery
by: Limon, David, et al.
Published: (2017)
by: Limon, David, et al.
Published: (2017)
Asthma and allergic disease: their relation with Necator americanus and other helminth infections
by: Feary, Johanna Ruth
Published: (2012)
by: Feary, Johanna Ruth
Published: (2012)
Polymer versus cation of gel polymer electrolytes in the charge storage of asymmetric supercapacitors
by: Pal, Bhupender, et al.
Published: (2019)
by: Pal, Bhupender, et al.
Published: (2019)
Effects of virgin coconut oil as
adjunct therapy in the treatment of
allergic rhinitis
by: Zainuddin, Nazli
Published: (2012)
by: Zainuddin, Nazli
Published: (2012)
Investigating novel biopolymeric nanostructures for drug delivery
by: Haroosh, Hazim Jasim Mohammed
Published: (2014)
by: Haroosh, Hazim Jasim Mohammed
Published: (2014)
Microencapsulation of drug into biodegradable polymer as a novel drug delivery system
by: Mohamed, Farahidah, et al.
Published: (2011)
by: Mohamed, Farahidah, et al.
Published: (2011)
Microencapsulation of gentamicin into biodegradable polymer as a novel drug delivery system
by: Mohamed, Farahidah, et al.
Published: (2011)
by: Mohamed, Farahidah, et al.
Published: (2011)
Similar Items
-
Study on Liposomes Integrity and Delivery of siRNA to Lung Cancer
by: Aljasser, Abdullah
Published: (2024) -
Phosphonium polymethacrylates for siRNA delivery: effect of polymer and RNA structural parameters on polyplex assembly and gene knockdown
by: Loczenski Rose, Vanessa, et al.
Published: (2015) -
In-vitro investigations into endocytosis and silencing of siRNA-liposomes
by: ALSHEHRI, ABDULLAH ALI D
Published: (2017) -
Development and application of a linear polyamidoamine-SiRNA delivery system
by: Fathi, Zainab H
Published: (2018) -
Pathways of cellular internalisation of liposomes delivered siRNA and effects on siRNA engagement with target mRNA and silencing in cancer cells
by: Alshehri, Abdullah Ali, et al.
Published: (2018)