Investigating novel cationic polymers for siRNA delivery for treatment of allergic disease

Spleen tyrosine kinase (Syk) is an enzyme which plays a prominent role in IgE-dependent signal transduction in type 1 hypersensitivity reactions. Due to the important role of Syk in the early signalling cascade in mast cells and basophils for inducing allergic reaction, it could be a suitable target...

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Bibliographic Details
Main Author: Almughem, Fahad
Format: Thesis (University of Nottingham only)
Language:English
Published: 2018
Online Access:https://eprints.nottingham.ac.uk/52376/