Annexin A2 antibodies but not inhibitors of the annexin A2 heterotetramer impair productive HIV-1 infection of macrophages in vitro

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Annexin A2 antibodies but not inhibitors of the annexin A2 heterotetramer impair productive HIV-1 infection of macrophages in vitro

During sexual transmission of human immunodeficiency virus (HIV), macrophages are initial targets for HIV infection. Secretory leukocyte protease inhibitor (SLPI) has been shown to protect against HIV infection of macrophages through interactions with annexin A2 (A2), which is found on the macrophag...

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Bibliographic Details
Main Authors:	Woodham, Andrew W., Sanna, Adriana M., Taylor, Julia R., Skeate, Joseph G., Da Silva, Diane M., Dekker, Lodewijk V., Kast, W. Martin
Format:	Article
Published:	BioMed Central 2016
Subjects:	Annexin A2 heterotetramer HIV-1 Inhibitor Macrophage Receptor
Online Access:	https://eprints.nottingham.ac.uk/40840/

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