Annexin A2 antibodies but not inhibitors of the annexin A2 heterotetramer impair productive HIV-1 infection of macrophages in vitro

Annexin A2 antibodies but not inhibitors of the annexin A2 heterotetramer impair productive HIV-1 infection of macrophages in vitro

During sexual transmission of human immunodeficiency virus (HIV), macrophages are initial targets for HIV infection. Secretory leukocyte protease inhibitor (SLPI) has been shown to protect against HIV infection of macrophages through interactions with annexin A2 (A2), which is found on the macrophag...

Full description

Bibliographic Details
Main Authors: Woodham, Andrew W., Sanna, Adriana M., Taylor, Julia R., Skeate, Joseph G., Da Silva, Diane M., Dekker, Lodewijk V., Kast, W. Martin
Format: Article
Published: BioMed Central 2016
Subjects:
Annexin A2
heterotetramer
HIV-1
Inhibitor
Macrophage
Receptor
Online Access:https://eprints.nottingham.ac.uk/40840/

Internet

https://eprints.nottingham.ac.uk/40840/

Similar Items