Synthesis and Antibacterial Study of Aspirin-Chalcone Derivatives

The chemistry of aspirin and chalcone derivatives has been extensively studied and developed as one of the pharmaceutically important molecules. In this study, new aspirin-chalcone derivatives have been successfully synthesized and characterized via FTIR, 1H and 13C NMR spectroscopy. The antibacte...

Full description

Bibliographic Details
Main Authors:	Zainab, Ngaini, Ho, Doris Ai Hui, Hasnain, Hussain, Wan Sharifatun Handayani, binti Wan Zullkiplee, Meng, Guan Tay, Norhasnan, Sahari, Norsyafikah Asyilla, Nordin
Format:	Article
Language:	English
Published:	Universiti Malaysia Sarawak, (UNIMAS) 2013
Subjects:	QD Chemistry
Online Access:	http://ir.unimas.my/15567/ http://ir.unimas.my/15567/ http://ir.unimas.my/15567/1/Synthesis%20and%20Antibacterial%20Study%20of%20Aspirin%20%28abstract%29.pdf

id	unimas-15567
recordtype	eprints
spelling	unimas-155672017-03-15T10:33:03Z http://ir.unimas.my/15567/ Synthesis and Antibacterial Study of Aspirin-Chalcone Derivatives Zainab, Ngaini Ho, Doris Ai Hui Hasnain, Hussain Wan Sharifatun Handayani, binti Wan Zullkiplee Meng, Guan Tay Norhasnan, Sahari Norsyafikah Asyilla, Nordin QD Chemistry The chemistry of aspirin and chalcone derivatives has been extensively studied and developed as one of the pharmaceutically important molecules. In this study, new aspirin-chalcone derivatives have been successfully synthesized and characterized via FTIR, 1H and 13C NMR spectroscopy. The antibacterial activities of synthesized compounds were investigated towards Escherichia coli ATCC 8739 via turbidimetric kinetic method. The newly synthesized aspirin-chalcone derivatives, however showed poor antibacterial activity against E. coli ATCC 8739 at the concentration of 50, 80 and 100 ppm. The effect of the molecular structure of the synthesized compounds on the antibacterial activity is discussed. Universiti Malaysia Sarawak, (UNIMAS) 2013 Article PeerReviewed text en http://ir.unimas.my/15567/1/Synthesis%20and%20Antibacterial%20Study%20of%20Aspirin%20%28abstract%29.pdf Zainab, Ngaini and Ho, Doris Ai Hui and Hasnain, Hussain and Wan Sharifatun Handayani, binti Wan Zullkiplee and Meng, Guan Tay and Norhasnan, Sahari and Norsyafikah Asyilla, Nordin (2013) Synthesis and Antibacterial Study of Aspirin-Chalcone Derivatives. Borneo Journal of Resource Science and Technology, 3 (1). pp. 52-57. ISSN 2229-9769 https://www.researchgate.net/publication/291336657_Synthesis_and_Antibacterial_Study_of_Aspirin-Chalcone_Derivatives
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Sarawak
building	UNIMAS Institutional Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Zainab, Ngaini Ho, Doris Ai Hui Hasnain, Hussain Wan Sharifatun Handayani, binti Wan Zullkiplee Meng, Guan Tay Norhasnan, Sahari Norsyafikah Asyilla, Nordin Synthesis and Antibacterial Study of Aspirin-Chalcone Derivatives
description	The chemistry of aspirin and chalcone derivatives has been extensively studied and developed as one of the pharmaceutically important molecules. In this study, new aspirin-chalcone derivatives have been successfully synthesized and characterized via FTIR, 1H and 13C NMR spectroscopy. The antibacterial activities of synthesized compounds were investigated towards Escherichia coli ATCC 8739 via turbidimetric kinetic method. The newly synthesized aspirin-chalcone derivatives, however showed poor antibacterial activity against E. coli ATCC 8739 at the concentration of 50, 80 and 100 ppm. The effect of the molecular structure of the synthesized compounds on the antibacterial activity is discussed.
format	Article
author	Zainab, Ngaini Ho, Doris Ai Hui Hasnain, Hussain Wan Sharifatun Handayani, binti Wan Zullkiplee Meng, Guan Tay Norhasnan, Sahari Norsyafikah Asyilla, Nordin
author_facet	Zainab, Ngaini Ho, Doris Ai Hui Hasnain, Hussain Wan Sharifatun Handayani, binti Wan Zullkiplee Meng, Guan Tay Norhasnan, Sahari Norsyafikah Asyilla, Nordin
author_sort	Zainab, Ngaini
title	Synthesis and Antibacterial Study of Aspirin-Chalcone Derivatives
title_short	Synthesis and Antibacterial Study of Aspirin-Chalcone Derivatives
title_full	Synthesis and Antibacterial Study of Aspirin-Chalcone Derivatives
title_fullStr	Synthesis and Antibacterial Study of Aspirin-Chalcone Derivatives
title_full_unstemmed	Synthesis and Antibacterial Study of Aspirin-Chalcone Derivatives
title_sort	synthesis and antibacterial study of aspirin-chalcone derivatives
publisher	Universiti Malaysia Sarawak, (UNIMAS)
publishDate	2013
url	http://ir.unimas.my/15567/ http://ir.unimas.my/15567/ http://ir.unimas.my/15567/1/Synthesis%20and%20Antibacterial%20Study%20of%20Aspirin%20%28abstract%29.pdf
first_indexed	2018-09-06T16:23:11Z
last_indexed	2018-09-06T16:23:11Z
_version_	1610875920098263040

Synthesis and Antibacterial Study of Aspirin-Chalcone Derivatives

Similar Items