Enterovirus 71 in Malaysia: A decade later

In the last decade, Malaysia has experienced several hand, foot and mouth disease (HFMD) epidemics, complicated by fatalities due to severe neurological involvement. Enterovirus 71 (EV-71) has been implicated as the major causative agent for these epidemics. EV-71 infection is a global public health...

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Main Authors: Chan, Y.F., Sam, I.C., Wee, K.L., AbuBakar, S.
Format: Article
Published: 2011
Subjects:
Online Access:http://eprints.um.edu.my/7327/
http://eprints.um.edu.my/7327/1/Enterovirus_71_in_Malaysia%2D_A_decade_later.pdf
id um-7327
recordtype eprints
spelling um-73272017-11-07T08:48:22Z Enterovirus 71 in Malaysia: A decade later Chan, Y.F. Sam, I.C. Wee, K.L. AbuBakar, S. R Medicine In the last decade, Malaysia has experienced several hand, foot and mouth disease (HFMD) epidemics, complicated by fatalities due to severe neurological involvement. Enterovirus 71 (EV-71) has been implicated as the major causative agent for these epidemics. EV-71 infection is a global public health problem with pandemic potential. In many parts of Asia-Pacific, the virus has emerged as one of the most deadly virus infections amongst young children. The virus is highly transmissible through faecal-oral route and respiratory droplets. A recent rise in neurological complications and deaths suggests that the viruses currently circulating may be more virulent. The major risk factor associated with more severe EV-71 infection is young age and poor cellular immunity. Rapid laboratory diagnosis and molecular surveillance is important to closely monitor the emergence of new EV-71 subgenotypes. Since vaccine and anti-virals for EV-71 are not available, control and prevention strategies remain the only ways to combat the infection. 2011 Article PeerReviewed application/pdf http://eprints.um.edu.my/7327/1/Enterovirus_71_in_Malaysia%2D_A_decade_later.pdf Chan, Y.F.; Sam, I.C.; Wee, K.L.; AbuBakar, S. (2011) Enterovirus 71 in Malaysia: A decade later. Neurology Asia <http://eprints.um.edu.my/view/publication/Neurology_Asia.html>, 16 (1). pp. 1-15. ISSN 1823-6138 http://eprints.um.edu.my/7327/
repository_type Digital Repository
institution_category Local University
institution University Malaya
building UM Research Repository
collection Online Access
topic R Medicine
spellingShingle R Medicine
Chan, Y.F.
Sam, I.C.
Wee, K.L.
AbuBakar, S.
Enterovirus 71 in Malaysia: A decade later
description In the last decade, Malaysia has experienced several hand, foot and mouth disease (HFMD) epidemics, complicated by fatalities due to severe neurological involvement. Enterovirus 71 (EV-71) has been implicated as the major causative agent for these epidemics. EV-71 infection is a global public health problem with pandemic potential. In many parts of Asia-Pacific, the virus has emerged as one of the most deadly virus infections amongst young children. The virus is highly transmissible through faecal-oral route and respiratory droplets. A recent rise in neurological complications and deaths suggests that the viruses currently circulating may be more virulent. The major risk factor associated with more severe EV-71 infection is young age and poor cellular immunity. Rapid laboratory diagnosis and molecular surveillance is important to closely monitor the emergence of new EV-71 subgenotypes. Since vaccine and anti-virals for EV-71 are not available, control and prevention strategies remain the only ways to combat the infection.
format Article
author Chan, Y.F.
Sam, I.C.
Wee, K.L.
AbuBakar, S.
author_facet Chan, Y.F.
Sam, I.C.
Wee, K.L.
AbuBakar, S.
author_sort Chan, Y.F.
title Enterovirus 71 in Malaysia: A decade later
title_short Enterovirus 71 in Malaysia: A decade later
title_full Enterovirus 71 in Malaysia: A decade later
title_fullStr Enterovirus 71 in Malaysia: A decade later
title_full_unstemmed Enterovirus 71 in Malaysia: A decade later
title_sort enterovirus 71 in malaysia: a decade later
publishDate 2011
url http://eprints.um.edu.my/7327/
http://eprints.um.edu.my/7327/1/Enterovirus_71_in_Malaysia%2D_A_decade_later.pdf
first_indexed 2018-09-06T05:25:33Z
last_indexed 2018-09-06T05:25:33Z
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