Enterovirus 71 in Malaysia: A decade later
In the last decade, Malaysia has experienced several hand, foot and mouth disease (HFMD) epidemics, complicated by fatalities due to severe neurological involvement. Enterovirus 71 (EV-71) has been implicated as the major causative agent for these epidemics. EV-71 infection is a global public health...
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um-73272017-11-07T08:48:22Z Enterovirus 71 in Malaysia: A decade later Chan, Y.F. Sam, I.C. Wee, K.L. AbuBakar, S. R Medicine In the last decade, Malaysia has experienced several hand, foot and mouth disease (HFMD) epidemics, complicated by fatalities due to severe neurological involvement. Enterovirus 71 (EV-71) has been implicated as the major causative agent for these epidemics. EV-71 infection is a global public health problem with pandemic potential. In many parts of Asia-Pacific, the virus has emerged as one of the most deadly virus infections amongst young children. The virus is highly transmissible through faecal-oral route and respiratory droplets. A recent rise in neurological complications and deaths suggests that the viruses currently circulating may be more virulent. The major risk factor associated with more severe EV-71 infection is young age and poor cellular immunity. Rapid laboratory diagnosis and molecular surveillance is important to closely monitor the emergence of new EV-71 subgenotypes. Since vaccine and anti-virals for EV-71 are not available, control and prevention strategies remain the only ways to combat the infection. 2011 Article PeerReviewed application/pdf http://eprints.um.edu.my/7327/1/Enterovirus_71_in_Malaysia%2D_A_decade_later.pdf Chan, Y.F.; Sam, I.C.; Wee, K.L.; AbuBakar, S. (2011) Enterovirus 71 in Malaysia: A decade later. Neurology Asia <http://eprints.um.edu.my/view/publication/Neurology_Asia.html>, 16 (1). pp. 1-15. ISSN 1823-6138 http://eprints.um.edu.my/7327/ |
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R Medicine Chan, Y.F. Sam, I.C. Wee, K.L. AbuBakar, S. Enterovirus 71 in Malaysia: A decade later |
description |
In the last decade, Malaysia has experienced several hand, foot and mouth disease (HFMD) epidemics, complicated by fatalities due to severe neurological involvement. Enterovirus 71 (EV-71) has been implicated as the major causative agent for these epidemics. EV-71 infection is a global public health problem with pandemic potential. In many parts of Asia-Pacific, the virus has emerged as one of the most deadly virus infections amongst young children. The virus is highly transmissible through faecal-oral route and respiratory droplets. A recent rise in neurological complications and deaths suggests that the viruses currently circulating may be more virulent. The major risk factor associated with more severe EV-71 infection is young age and poor cellular immunity. Rapid laboratory diagnosis and molecular surveillance is important to closely monitor the emergence of new EV-71 subgenotypes. Since vaccine and anti-virals for EV-71 are not available, control and prevention strategies remain the only ways to combat the infection. |
format |
Article |
author |
Chan, Y.F. Sam, I.C. Wee, K.L. AbuBakar, S. |
author_facet |
Chan, Y.F. Sam, I.C. Wee, K.L. AbuBakar, S. |
author_sort |
Chan, Y.F. |
title |
Enterovirus 71 in Malaysia: A decade later |
title_short |
Enterovirus 71 in Malaysia: A decade later |
title_full |
Enterovirus 71 in Malaysia: A decade later |
title_fullStr |
Enterovirus 71 in Malaysia: A decade later |
title_full_unstemmed |
Enterovirus 71 in Malaysia: A decade later |
title_sort |
enterovirus 71 in malaysia: a decade later |
publishDate |
2011 |
url |
http://eprints.um.edu.my/7327/ http://eprints.um.edu.my/7327/1/Enterovirus_71_in_Malaysia%2D_A_decade_later.pdf |
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2018-09-06T05:25:33Z |
last_indexed |
2018-09-06T05:25:33Z |
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1610834544601071616 |