3′,4′-dihydroxyflavonol ameliorates endoplasmic reticulum stress-induced apoptosis and endothelial dysfunction in mice

3′,4′-dihydroxyflavonol ameliorates endoplasmic reticulum stress-induced apoptosis and endothelial dysfunction in mice

Endoplasmic reticulum (ER) stress has been implicated in the development of hypertension 3 through the induction of endothelial impairment. As 3′,4′-dihydroxyflavonol (DiOHF) 4 reduces vascular injury caused by ischaemia/reperfusion or diabetes, and flavonols have been demonstrated to attenuate ER s...

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Bibliographic Details
Main Authors: Lau, Y.S., Mustafa, M.R., Choy, K.W., Chan, S.M.H., Potocnik, S., Herbert, T.P., Woodman, O.L.
Format: Article
Published: Nature Publishing Group 2018
Subjects:
Q Science (General)
R Medicine
Online Access:http://dx.doi.org/10.1038/s41598-018-19584-8
http://dx.doi.org/10.1038/s41598-018-19584-8
http://eprints.um.edu.my/18976/1/3%E2%80%B2%2C4%E2%80%B2%2Ddihydroxyflavonol_ameliorates_endoplasmic_reticulum_stress%2Dinduced_apoptosis_and_endothelial_dysfunction_in_mice.pdf

Internet

http://dx.doi.org/10.1038/s41598-018-19584-8
http://dx.doi.org/10.1038/s41598-018-19584-8
http://eprints.um.edu.my/18976/1/3%E2%80%B2%2C4%E2%80%B2%2Ddihydroxyflavonol_ameliorates_endoplasmic_reticulum_stress%2Dinduced_apoptosis_and_endothelial_dysfunction_in_mice.pdf

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