Angiotensin 1-7 protects against Angiotensin II-Induced Endoplasmic Reticulum Stress and Endothelial Dysfunction via Mas Receptor

Angiotensin 1-7 (Ang 1-7) counter-regulates the cardiovascular actions of angiotensin II (Ang II). The present study investigated the protective effect of Ang 1-7 against Ang II-induced endoplasmic reticulum (ER) stress and endothelial dysfunction. Ex vivo treatment with Ang II (0.5 mu M, 24 hours)...

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Bibliographic Details
Main Authors: Murugan, D., Lau, Y.S., Lau, W.C., Mustafa, M.R., Huang, Y.
Format: Article
Published: Public Library of Science 2015
Subjects:
Online Access:DOI: 10.1371/journal.pone.0145413
DOI: 10.1371/journal.pone.0145413