Mms22p protects Saccharomyces cerevisiae from DNA damage induced by topoisomerase II
The cleavage reaction of topoisomerase II, which creates double-stranded DNA breaks, plays a central role in both the cure and initiation of cancer. Therefore, it is important to understand the cellular processes that repair topoisomerase II-generated DNA damage. Using a genome-wide approach with Sa...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Oxford University Press
2005
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549411/ |