Mms21 SUMO Ligase Activity Promotes Nucleolar Function in Saccharomyces cerevisiae
The budding yeast E3 SUMO ligase Mms21, also known as Nse2, is a component of the Smc5/6 complex, which regulates sister chromatid cohesion, DNA replication, and repair. Our study shows that the mms21RINGΔ mutant exhibits (1) reduced ribosomal RNA production; (2) nuclear accumulation of ribosomal pr...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Genetics Society of America
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068852/ |