Alginate Oligosaccharide Prevents Acute Doxorubicin Cardiotoxicity by Suppressing Oxidative Stress and Endoplasmic Reticulum-Mediated Apoptosis

Alginate Oligosaccharide Prevents Acute Doxorubicin Cardiotoxicity by Suppressing Oxidative Stress and Endoplasmic Reticulum-Mediated Apoptosis

Doxorubicin (DOX) is a highly potent chemotherapeutic agent, but its usage is limited by dose-dependent cardiotoxicity. DOX-induced cardiotoxicity involves increased oxidative stress and activated endoplasmic reticulum-mediated apoptosis. Alginate oligosaccharide (AOS) is a non-immunogenic, non-toxi...

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Bibliographic Details
Main Authors: Guo, Jun-Jie, Ma, Lei-Lei, Shi, Hong-Tao, Zhu, Jian-Bing, Wu, Jian, Ding, Zhi-Wen, An, Yi, Zou, Yun-Zeng, Ge, Jun-Bo
Format: Online
Language:English
Published: MDPI 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192468/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192468/

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