Validation of an LC-MS/MS Method for Urinary Lactulose and Mannitol Quantification: Results in Patients with Irritable Bowel Syndrome

Aim. Lactulose/mannitol ratio is used to assess intestinal barrier function. Aim of this work was to develop a robust and rapid method for the analysis of lactulose and mannitol in urine by liquid chromatography coupled to tandem mass spectrometry. Lactulose/mannitol ratio has been measured in pedi...

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Bibliographic Details
Main Authors: Gervasoni, Jacopo, Schiattarella, Arcangelo, Giorgio, Valentina, Primiano, Aniello, Russo, Consuelo, Tesori, Valentina, Scaldaferri, Franco, Urbani, Andrea, Zuppi, Cecilia, Persichilli, Silvia
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192291/