Initiation of Meiotic Recombination in Mammals

Meiotic recombination is initiated by the induction of programmed DNA double strand breaks (DSBs). DSB repair promotes homologous interactions and pairing and leads to the formation of crossovers (COs), which are required for the proper reductional segregation at the first meiotic division. In mamma...

Full description

Bibliographic Details
Main Authors: Kumar, Rajeev, de Massy, Bernard
Format: Online
Language:English
Published: MDPI 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966222/