PKCι regulates nuclear YAP1 localization and ovarian cancer tumorigenesis

Atypical protein kinase Cι (PKCι) is an oncogene in lung and ovarian cancer. The PKCι gene PRKCI is targeted for frequent tumor-specific copy number gain (CNG) in both lung squamous cell carcinoma (LSCC) and ovarian serous carcinoma (OSC). We recently demonstrated that in LSCC cells PRKCI CNG functi...

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Bibliographic Details
Main Authors: Wang, Yin, Justilien, Verline, Brennan, Katharyn I., Jamieson, Lee, Murray, Nicole R., Fields, Alan P.
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173453/