PKCι depletion initiates mitotic slippage-induced senescence in glioblastoma

Cellular senescence is a tumor suppressor mechanism where cells enter a permanent growth arrest following cellular stress. Oncogene-induced senescence (OIS) is induced in non-malignant cells following the expression of an oncogene or inactivation of a tumor suppressor. Previously, we have shown that...

Full description

Bibliographic Details
Main Authors: Restall, Ian J, Parolin, Doris A E, Daneshmand, Manijeh, Hanson, Jennifer E L, Simard, Manon A, Fitzpatrick, Megan E, Kumar, Ritesh, Lavictoire, Sylvie J, Lorimer, Ian A J
Format: Online
Language:English
Published: Taylor & Francis 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825548/