Regulation of GPCR expression through an interaction with CCT7, a subunit of the CCT/TRiC complex
A direct and functional interaction between a subunit of the CCT/TCP-1 ring complex (TRiC) chaperonin complex and G protein–coupled receptor (GPCRs) is shown. Evidence is provided that distinct nascent GPCRs can undergo alternative folding pathways and that CCT/TRiC is critical in preventing aggrega...
| Main Authors: | , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170604/ |